SEDATION AND ANALGESIA

This study is testing two different approaches to sedation for people with severe COPD who need help breathing from a ventilator. Researchers want to see if using no sedation at all or briefly stopping sedation each day helps patients spend fewer days on the breathing machine. Th…

This study aims to find better ways to manage pain in children who need breathing machines. Researchers are testing if common non-opioid medications (IV Tylenol and Toradol) can reduce pain and decrease the need for strong opioid drugs. About 644 children aged 2 months to 17 year…

This study aims to find out if one of two commonly used pain and sedation medicines (fentanyl or hydromorphone) is better for adults in the intensive care unit (ICU) who are on a breathing machine. Researchers will compare how much total pain medicine patients need, how long they…

This study aims to find out how common pain is for sedated patients in intensive care who are on breathing machines. Researchers will observe 370 patients to see if pain is linked to longer hospital stays, difficulty coming off the ventilator, or risk of death. The study does not…

This study is testing whether certain radiology procedures can be done safely using deep sedation instead of general anesthesia. Researchers want to see if a sedation method led by the radiology team can work well when anesthesia specialists are in short supply. They'll test this…

This study aims to better understand how two common anesthesia drugs affect a patient's brain waves and stress response during a specific medical procedure called an ERCP. Researchers will monitor 20 patients using special sensors on the forehead and chest while they are under an…

This study aims to understand how regular cannabis use affects sedation during wisdom tooth surgery. Researchers will compare two groups—cannabis users and non-users—measuring how much anesthesia medication they need and how their bodies respond during the procedure. The goal is …