Renji Hospital

This study compares three different ways to remove blood clots from deep leg veins. About 210 adults with recent deep vein thrombosis (DVT) will be assigned to one of three access points for the procedure. The goal is to see which method works best and reduces the chance of long-…

This study looks at whether taking the targeted drug pyrotinib continuously or only at certain times works better to keep HER2-positive breast cancer from coming back. About 488 adults who have already had initial treatment will be randomly assigned to one of the two schedules. T…

This study looks at whether long-term exercise training can improve daily function and heart-lung health in people with pulmonary hypertension, a condition where blood pressure in the lungs is too high. About 104 adults who are stable on medication will take part. The goal is to …

This study tests a combination of three drugs (adebrelimab, etoposide, and cisplatin) given before surgery for a rare and aggressive type of bladder cancer. About 22 adults aged 18-75 with neuroendocrine bladder carcinoma will receive up to 4 cycles of treatment. The main goals a…

This study tests a special filter device placed in the leg artery during a procedure to remove plaque. The filter catches any debris that might break loose, preventing it from blocking smaller blood vessels downstream. The goal is to see if using this filter reduces complications…

This study tests whether adding the drug serplulimab to standard chemotherapy before surgery can eliminate all signs of triple-negative breast cancer in 46 women. Participants receive the combination weekly, then have surgery to check if the cancer is gone. The goal is to see if …

This study tests whether tranexamic acid, a drug that helps blood clot, can reduce blood loss during liver transplant surgery without causing dangerous clots. About 1,546 adults receiving a new liver will be randomly given either the drug or a placebo. The goal is to see if the d…

This study looks at how well the drug Disitamab vedotin works and how safe it is for people with breast cancer. It includes 45 patients who have used this drug before or are currently using it. The main goal is to see how long the cancer stays under control before it grows again.

This study tests if washing out infected fluid from the brain's cavities (ventricular irrigation) can help treat ventriculitis, a severe brain infection with a high death rate. About 310 adults aged 18-65 with confirmed ventriculitis will either receive standard antibiotic care o…

This study tests whether adding the drug pyrotinib to standard trastuzumab therapy can further reduce the chance of breast cancer returning in women with HER2-positive breast cancer who still have cancer cells after initial chemotherapy and anti-HER2 treatment. About 316 women wi…

This study tests whether two drugs, disitamab vedotin and tislelizumab, given before surgery can help control high-risk upper tract urothelial carcinoma while allowing surgeons to remove only the tumor and keep the kidney. About 20 participants will receive the drugs every 3 week…

This study tests a new drug called QL1706 (a mix of two immune-boosting medicines) combined with standard chemotherapy given before surgery for people with a common type of breast cancer (HR-positive, HER2-negative). The goal is to see if this combination can eliminate all cancer…

This study looks at how well and how safely the drug dalpiciclib works for people with a certain type of advanced breast cancer (HR+/HER2-). About 103 participants will take the drug, and researchers will track how long the cancer stays under control and any side effects. The goa…

This study tests a drug called Disitamab vedotin in 36 women with advanced breast cancer that has low HER2 levels and has spread. Participants have had only one previous chemotherapy and no prior antibody-drug treatments. The goal is to see if the drug can shrink tumors and contr…

This study is testing two new imaging agents that light up breast cancer cells on PET scans. Researchers want to see if these agents can find tumors and their spread more accurately than current methods. About 200 women with breast cancer or suspected breast cancer will receive t…

This study aims to improve how doctors see digestive system cancers (like liver, stomach, and pancreatic cancer) using special PET/CT imaging probes. Researchers will test these probes in 400 adults to measure how they spread in the body and how well they find tumors. The goal is…

This study is testing a new type of PET scan that targets a protein called Trop2, found on many solid tumors. The goal is to see if this scan can find and stage cancers like bladder, lung, liver, and ovarian cancer better than current methods. About 400 adults with confirmed or s…

This study aims to see if a new imaging agent called [18F]RCCB6 can improve PET/CT scans for diagnosing kidney cancer, especially the most common type (clear cell renal cell carcinoma). About 300 adults with confirmed or suspected kidney cancer will receive the agent and undergo …

This study tests special PET scans that light up pancreatic cancer cells, helping doctors see where the cancer is and whether targeted drugs might work. About 90 people with pancreatic cancer will receive a radioactive tracer before treatment. The goal is to improve detection and…

This study tests a new type of PET/CT scan that looks for a protein called CD70 on cancer cells. It aims to better detect kidney cancer, lymphoma, and nasopharyngeal cancer in 300 adults. The scan may help doctors see tumors more clearly and guide treatment decisions.

This early study tests a new way to help the heart pump by pacing the diaphragm through a vein near the heart. Ten heart failure patients already scheduled for a standard heart device will also receive this temporary pacing. The goal is to see if it's safe and can improve heart f…

This study looks at a rare but serious side effect—acute pancreatitis—that can happen after a procedure to remove blood clots (mechanical thrombectomy). Researchers will review medical records of about 10 patients to find out how often this complication occurs, what patient or pr…

This study follows 275 infants who received a liver transplant to see how they grow and develop over time. Researchers want to understand growth patterns so they can create better follow-up plans. The study does not test a new treatment but gathers information to improve care.

This study looks at whether tiny bits of tumor DNA found in blood and urine can help doctors detect if cancer is still present or coming back after surgery for a rare type of bladder and kidney cancer. About 84 adults who have had their kidney and ureter removed will provide bloo…

This study follows 369 liver transplant patients who have new or worsening kidney problems. Researchers perform kidney biopsies to understand the cause of kidney damage and track how kidney function changes over time. The goal is to identify risk factors that lead to kidney failu…

This study uses a special PET scan to see if a heart valve procedure called TAVI can reverse scarring and damage in the heart muscle of people with severe aortic stenosis. About 25 patients will be scanned before and 6 months after TAVI, and compared to a group not getting the pr…

This study is testing a special device (GILUPI CellCollector) that captures cancer cells from the blood of women who have already had surgery and chemotherapy for breast cancer. The goal is to see if the number of these circulating tumor cells can help predict whether the cancer …

This study follows 2,000 people with a type of brain bleed (epidural hematoma) after a head injury. Researchers want to see which surgery works best for recovery. Participants are treated at multiple hospitals in China, and their progress is tracked for up to 6 months.

This study is following 10,000 adults aged 18 and older to learn how muscle loss (sarcopenia), metabolic diseases, and aging are connected. Researchers will collect health data, lifestyle info, and biosamples over time. The goal is to understand how these factors together affect …

This study looks at 3,000 people with primary biliary cholangitis (PBC) to see if changes in a blood marker called alkaline phosphatase after treatment are linked to better survival without serious liver problems. Researchers will track participants over time to build a model tha…

This study looks at how well breast cancer responds to treatment given before surgery and how that affects long-term survival. Researchers will compare different treatment plans and patient characteristics in 488 women with early or advanced breast cancer. The goal is to find whi…