Renji Hospital

This study looks at how well minimally invasive procedures (like angioplasty and stents) work for people with severe blockages in the leg arteries. Researchers will follow 1000 patients to see if the treatments restore blood flow, keep arteries open, and reduce the need for repea…

This study compares two types of brain surgery for people with a severe head injury that causes a blood clot (epidural hematoma) and brain herniation. One surgery removes the clot and a piece of skull to relieve pressure, while the other only removes the clot. The goal is to see …

This study tests two drugs, fruquintinib and serplulimab, as the first treatment for people with a rare type of kidney cancer that has spread or cannot be removed. The goal is to see if the combination can shrink tumors or slow the disease. About 39 adults with no prior treatment…

This study tests whether combining two drugs, lenvatinib and VIC-1911, can safely shrink tumors and slow cancer growth in people with advanced liver cancer. About 12 adults aged 18-75 with stage C liver cancer and good liver function are taking part. The goal is to see how well t…

This study tests a combination of two drugs, cadonilimab and lenvatinib, in people with advanced clear cell kidney cancer whose disease got worse after initial immunotherapy. The goal is to see if this combo can shrink tumors or stop them from growing. About 28 adults will take p…

This study tests whether adding the targeted drug pyrotinib to standard chemotherapy and trastuzumab before surgery can completely eliminate tumors in women with HER2-positive early breast cancer. About 53 women with stage II to III breast cancer will receive the combination for …

This early-phase study tests a single dose of YOLT-202 in 18 adults with Alpha-1 antitrypsin deficiency (AATD), a genetic condition that can damage the lungs and liver. The main goal is to check if the drug is safe and to find the best dose. Participants must have the severe PiZZ…

This study aims to create computer models that predict how long patients with advanced pancreatic cancer might live and how well they respond to chemotherapy. Researchers will use medical images, tissue samples, and genetic information from 100 participants. The goal is to help d…