Oregon Health And Science University

This study compares the antibiotic cefotetan to standard treatments for E. coli infections in the blood or urinary tract. About 84 hospitalized adults will be randomly assigned to receive either cefotetan or usual care. The goal is to see if cefotetan works as well or better at c…

This study tests two types of progestin-only birth control pills (drospirenone and norethindrone) to see which one helps control high blood pressure better in women who had preeclampsia during pregnancy. About 50 participants will take one of the pills for 6 weeks after leaving t…

This study tests a smartphone app called DailyDose that helps people with type 1 diabetes manage their blood sugar. The app uses data from a continuous glucose monitor, insulin use, and exercise to give personalized advice on insulin doses and carbs during exercise or low blood s…

This study tests a procedure called FETO, where a tiny balloon is placed in the windpipe of a fetus to help the lungs grow. It is for babies with a severe form of congenital diaphragmatic hernia, a birth defect where the diaphragm has a hole. The trial will compare survival rates…

This study tests whether matching specific drugs to a person's unique type of type 1 diabetes can better protect their heart and kidneys. About 57 adults with type 1 diabetes and early signs of heart or kidney issues will receive targeted treatments. The goal is to slow or preven…

This study looks at how Rocklatan eye drops affect blood flow in the eyes of people with early-stage glaucoma. About 30 participants will use the drops and have their eye blood flow measured with special imaging over 6 to 12 months. The goal is to see if the drops and the imaging…

This study tests whether offering gift cards can help people leaving jail stay on their medication for opioid use disorder. Participants earn rewards for attending appointments and counseling sessions for up to three months after release. The goal is to see if this approach is pr…

This study tests whether a leadership training program can help National Guard leaders better support their team members' mental health. About 5,400 leaders, service members, and their spouses will take part. The training includes a one-hour online course, a behavior tracking exe…

This study tests a training program for therapists to help them use powered mobility devices (like small motorized chairs) with young children (ages 1-2) who have severe cerebral palsy. The goal is to see if this training is practical and helpful for therapists, families, and chi…

This early-stage study will test whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with talk therapy is a safe and practical way to help women with long-term pelvic pain. Fifteen women aged 18–45 who have not gotten relief from standard treat…

This study aims to help people with mild traumatic brain injury (concussion) who have ongoing balance problems. Researchers will develop a new exercise program that focuses on how the body responds to imbalance, and compare it to standard balance therapy. The study will involve 8…

This study tests whether a weekly one-hour online group therapy called Center M can reduce symptoms of depression in pregnant women and new mothers. About 160 participants will either join Center M or receive standard care. The therapy is based on mindfulness and cognitive behavi…

This study tests a decision-making tool that helps doctors give brief behavioral counseling to parents of children aged 18-65 months with common behavior concerns. About 60 parents will receive guidance during a single medical or behavioral health visit. The goal is to see if thi…

This study looks at whether virtual reality (VR) construction tasks can show changes in performance caused by lack of sleep. Researchers will have 12 healthy adults do VR tasks and monitor their sleep. The goal is to see if VR can tell the difference between being tired and just …

This study looks at whether quick, bedside heart tests (ultrasound, EKG, and blood tests) can reliably detect heart problems in pregnant women who regularly use methamphetamine. Researchers will compare these simple tests to a full heart ultrasound. The goal is to find a faster, …

This study will give 40 pregnant people a Garmin Vivosmart 5 activity tracker to see if it's a useful tool for measuring and encouraging physical activity during pregnancy. Researchers want to learn how often people wear the device and if they find it helpful. The goal is to gath…

This study will test the Dexcom Stelo, an over-the-counter continuous glucose monitor, in 50 women who had gestational diabetes in their most recent pregnancy. The goal is to see how well the device works after childbirth and gather information on blood sugar patterns. Participan…