Oregon Health And Science University

This study tested a new automated system that delivers both insulin and pramlintide to manage blood sugar in people with type 1 diabetes. Pramlintide slows digestion to prevent high blood sugar after meals. The system used a continuous glucose monitor to automatically control two…

This study tested a vitamin metabolite in 77 people with PKAN, a rare genetic disorder that affects movement and brain function. The main goal was to see if the study product is safe and tolerable, and to measure any changes in the disease. Researchers also looked at gene express…

This study tested a new artificial pancreas system that automatically detects and delivers insulin for missed meals in people with type 1 diabetes. 29 adults used the new system or their usual pump for comparison. The goal was to see if the new algorithm keeps blood sugar in a he…

This pilot study looked at whether giving the diabetes drug metformin around the time of hip or knee replacement surgery is feasible and helps control blood sugar. Forty adults, with or without diabetes, were randomly assigned to receive metformin or a placebo. The main goal was …

This study tested a program where a nurse visits low-income women at home to provide birth control pills or shots. The goal was to see if this approach reduces unwanted pregnancies. The study included 103 women who were not pregnant and wanted to delay pregnancy.

This study tested whether a procedure called ERCP with sphincterotomy can lower the risk of repeat pancreatitis attacks in people with pancreas divisum, a condition where the pancreas has an unusual duct structure. 181 adults who had at least two pancreatitis episodes were random…

This study looked at whether giving children with severe wheezing two common asthma medicines (ipratropium and dexamethasone) in the ambulance can help them feel better faster and avoid going to the hospital. The trial included 44 children aged 2 to 17 who called 911 for breathin…

This study looked at whether keeping blood pressure higher (85-90 mmHg) for a week after a spinal cord injury helps people recover movement and feeling better than standard care (65-70 mmHg). 94 adults with new spinal cord injuries took part. The goal was to see if a higher blood…

This study looked at whether a special scope procedure (EUS plus ERCP) can reduce belly pain in people with long-term pancreatitis and blocked pancreatic ducts. Fourteen adults with moderate to severe pain took part. The goal was to see if clearing the duct with endoscopy improve…

This study tested a video-based support program for family caregivers of people with frontotemporal dementia (FTD). Sixteen caregivers participated to see if the program could reduce their stress and improve their quality of life. The goal was to help caregivers better manage cha…

This study tested a smartphone app called Center M that delivers mindfulness-based therapy to pregnant people with depression. 116 participants were randomly assigned to use the app or receive standard care. The goal was to see if the app could improve depression screening and re…

This study tested a personalized surgical approach for children aged 2-18 with obstructive sleep apnea who have small tonsils or Down syndrome. Instead of the standard tonsil and adenoid removal, doctors used a sleep endoscopy to tailor the surgery to each child's specific airway…

This early-phase study looked at how oral THC (dronabinol) affects sleep in 18 adults—some who use cannabis frequently and others who rarely use it. Participants stayed in a sleep lab for four days and nights while researchers measured brain waves, heart rate, and blood pressure.…

This study tested a program where older Black caregivers, their loved ones with dementia, and a support person walk together while looking at old neighborhood photos on a tablet. The goal was to see if this combination of physical activity and social reminiscing could improve car…

This study tested a video-based program called Tele-STELLA that helps family caregivers of people with Alzheimer's or related dementias. The program connects caregivers with a guide to find ways to reduce upsetting behaviors in their loved ones. The goal was to lower caregiver st…

This study tested a new technique for people to remove their own IUDs at home. Thirty participants who were already coming to the clinic for IUD removal tried the method. The goal was to see how well it worked and what people thought about it.

This study tested two new ultrasound techniques—shear wave elastography and microvascular flow imaging—to see if they can better track how leg muscle injuries heal over time. Nine adults with leg injuries were scanned during their recovery, and their function was measured with a …

This study looked at whether 8 weeks of yoga breathing practices can change how cerebrospinal fluid (CSF) moves around the brain and spine. 26 healthy adults who had never done yoga or similar practices were randomly assigned to one of two breathing groups. Researchers measured C…