Oregon Health And Science University

This study tests a digital app called COACH that helps patients with high blood pressure track their readings at home and share them with their doctor. The goal is to see if using the app leads to better blood pressure control compared to usual care. About 550 adults from primary…

This study tests whether using a chlorhexidine rinse after each bowel movement can reduce urinary tract infections (UTIs) in post-menopausal women who already use vaginal estrogen and have frequent UTIs. About 136 women aged 55-89 will be randomly assigned to either add the rinse…

This study tests whether offering incentives for achieving self-identified harm-reduction goals (like reducing use or seeking treatment) can lower overdose rates and increase engagement with services among people who use methamphetamine. Over 1,200 participants will be involved, …

This study tests a drug called clofazimine to see if it can help people with a stubborn lung infection caused by Mycobacterium avium complex (MAC). About 102 adults with confirmed MAC lung disease will receive the drug. The goal is to see if it clears the infection from sputum an…

This study looks at whether a special type of eye scan (functional OCT) can detect early signs of diabetic retinopathy, a leading cause of blindness. Currently, doctors use a dye injection to see blood vessel damage, but this dye can cause side effects. The study involves 165 peo…

This study tests a program designed to help new bus operators avoid weight gain and adjust to their jobs. About 284 new hires from several transit authorities will take part for two years. Some will receive the special program, while others will follow usual work practices. The g…

This study tests a special exercise program called TURN-IT designed to improve how people with Parkinson's disease turn, which is a common cause of falls. 55 participants with Parkinson's and a history of falls will either do the 6-week program or continue usual care. The goal is…

This study tests a program called COMPASS-NP for home care workers who have chronic pain. The program combines pain education, coping strategies, and work safety tips, led by a trained peer. Researchers want to see if it helps reduce how much pain interferes with work and daily l…

This study tests whether a virtual peer-support group led by transgender people who have had vaginoplasty helps others prepare for the same surgery. 290 trans adults seeking vaginoplasty will be randomly assigned to either the peer-support group or usual care with extra education…

This study looks at two ways to help children aged 1 to 10 years who have trouble swallowing due to a laryngeal cleft. One method injects a gel into the airway, the other uses stitches. The goal is to see which works better at stopping food and liquid from going into the lungs. A…

This study looked at how the body's internal clock affects heart disease risk in people with obesity. Researchers compared lean and overweight adults by measuring blood pressure and other heart markers at different times of day. Because only 17 people took part, the results are n…

This study tests a new type of eye scan called OCT angiography (OCTA) that doesn't require dye injections to see blood vessels in the eye. Researchers want to see if it can measure damage from diabetic retinopathy as well as or better than current methods. About 290 people with d…

This study checks how well sleep questionnaires work for children with Down syndrome, who often have sleep apnea. About 81 children aged 2-17 will fill out surveys, and their results will be compared to a standard sleep test. The goal is to find a simple way to spot sleep problem…

This study involves about 129 adults with rheumatic diseases (like arthritis) who are scheduled for a COVID-19 booster. Researchers want to see if getting the COVID-19 booster at the same time as other routine vaccines (like Tdap or hepatitis A) is as safe and effective as gettin…

This study was designed to see how well compounds from a standardized ashwagandha supplement are absorbed in healthy adults aged 65 and older. Researchers planned to measure levels of active ingredients in the blood after taking the supplement. However, the study was withdrawn be…