Oregon Health And Science University

This study tests whether using a dried blood spot test (a simple finger prick) can help people with hepatitis C start treatment faster than the usual method that requires a blood draw. The trial involves 141 participants who work with a peer support program and telemedicine. The …

This study tests a drug called clofazimine for people with a chronic lung infection caused by Mycobacterium avium complex (MAC). The goal is to see if adding clofazimine to standard treatment helps clear the bacteria from sputum and improves walking ability and fatigue. About 102…

This study tests a new app called COACH that helps patients and their doctors work together to control high blood pressure. The app connects home blood pressure readings to the patient's medical record and sends reminders based on behavioral science. About 550 adults with high bl…

This study tests whether offering incentives for achieving self-identified harm reduction goals (like completing overdose prevention training or setting daily life goals) can reduce overdose and increase treatment engagement among people who use methamphetamine. Over 1,200 partic…

This study tests whether using a chlorhexidine rinse after bowel movements can reduce urinary tract infections (UTIs) in post-menopausal women who already use vaginal estrogen and have frequent UTIs. About 136 women aged 55-89 will be randomly assigned to use either the chlorhexi…

This study tests a program to help new bus operators avoid gaining weight and succeed at work. About 284 new hires from several transit agencies will take part. Some will get the special program, while others follow usual routines. The goal is to see if the program helps them sta…

This pilot study tests whether a 4-week virtual mindfulness-based group intervention with social support is feasible and acceptable for pregnant individuals at higher risk for substance use. Participants join weekly video conference groups focused on grounding, thinking patterns,…

This Phase 3 trial tests whether a nurse-led phone program can help rural veterans better manage chronic pain. Over 600 participants will receive either the program or a one-time education session, and researchers will track pain interference for 12 months. The goal is to improve…

This study looks at whether virtual group support from peers who have had vaginoplasty can help transgender and non-binary people feel more prepared and less stressed before surgery. About 290 adults will be randomly assigned to either the peer support group or standard care with…

This study tests a program called COMPASS-NP for home care workers who have chronic pain. The program combines pain education, coping strategies, and safety tips, led by a trained peer. About 140 workers will take part to see if it reduces how much pain interferes with their work…

This study tests a special exercise program called TURN-IT for people with Parkinson's disease who have fallen in the past year. The program focuses on improving turning ability through targeted exercises. 55 participants will either do the program or continue usual care, and res…

This study looks at two different procedures to help children aged 1 to 10 years who have trouble swallowing due to a laryngeal cleft (a gap in the airway). One procedure injects a gel to build up the airway wall, the other uses stitches to close the gap. The goal is to see which…

Researchers are studying whether lowering the pressure inside the eye improves blood flow to the eye in people with glaucoma. The study follows adults with open-angle or chronic angle-closure glaucoma who are scheduled for glaucoma surgery. Using imaging scans, the team measures …

This study looks at how the body's internal clock (circadian rhythm) affects heart disease risk, especially in people with obesity. Researchers measured blood pressure and other heart markers in 17 lean and overweight adults over 5 days. The goal is to understand if obesity creat…

This study looks at how well COVID-19 booster vaccines work in people with rheumatic diseases (like arthritis) who take medications that affect their immune system. Researchers want to see if getting the COVID-19 booster at the same time as other routine vaccines (like tetanus or…

This study was designed to see how well compounds from a standardized ashwagandha supplement are absorbed in healthy adults aged 65 and older. Researchers planned to measure levels of active ingredients in the blood after taking the supplement. The study was withdrawn before enro…

This study checks whether sleep questionnaires can reliably detect obstructive sleep apnea (OSA) in children with Down syndrome, who are at higher risk for the condition. Researchers will compare questionnaire results with overnight sleep studies (the gold standard) in about 81 c…

This study is testing whether a special type of eye scan called functional OCT can detect early blood vessel damage in people with diabetic retinopathy. Currently, doctors use a dye injection to see these changes, which can cause side effects. The study will enroll 165 people wit…

This study tests a new type of eye scan called OCT angiography (OCTA) to see if it can better measure damage from diabetic retinopathy, a leading cause of vision loss. Researchers will compare OCTA images to standard dye-based tests in 290 people with diabetes. The goal is to fin…