Nyu Langone Health

This early-stage trial tested a vaccine called UB-312 in 8 adults with Parkinson's disease or multiple system atrophy (MSA). The goal was to see if the vaccine is safe and can trigger the immune system to produce antibodies against a harmful protein linked to these brain diseases…

This pilot study looked at whether limiting eating to either 6 or 10 hours per day helps adults maintain weight loss they achieved through a weight management program. 29 participants who had lost at least 5% of their body weight were randomly assigned to one of two time-restrict…

This study tested a program to help South Asian adults with uncontrolled diabetes lower their blood sugar. The program used health coaches, a patient registry, and referrals to community resources. 859 participants were followed for 6 months to see if their HbA1c levels dropped b…

This study tested a protein called FGF-2 to see if it can close long-lasting holes in the eardrum. 52 adults with a dry eardrum hole for at least 6 months received either FGF-2 or a placebo. The main goal was to see if the hole closed completely. If the placebo didn't work, parti…

This study tested a program where doctors, nurses, and medical assistants work together to help patients remember to take their blood pressure pills. Over 1,700 adults from 10 primary care clinics took part. The goal was to see if this team approach improves how often people take…

This study tested a program that connects community resources with doctor's offices to help South Asian adults with pre-diabetes lose weight. The goal was to prevent diabetes by helping participants lose at least 5% of their body weight in 6 months. Nearly 1,000 people took part …

This study tested whether using vancomycin powder and a diluted iodine wash during joint replacement surgery could prevent serious infections in high-risk patients. Over 2,100 adults with conditions like osteoarthritis who were at higher risk due to factors like smoking or obesit…

This study tested a program where community health workers screen Black men for early signs of high blood pressure, offer lifestyle advice, and connect them to doctors and social services. The goal is to prevent hypertension from getting worse. 430 Black men with elevated blood p…

This study tested a digital health platform called STABL that uses computer vision to guide knee rehabilitation at home after meniscectomy or synovectomy. 60 adults aged 18-65 who had knee surgery were randomly assigned to use STABL or attend in-person physical therapy. The goal …

This study looked at whether adding online educational modules before voice therapy helps people with voice problems stay engaged and attend sessions. Researchers compared three groups of adults with dysphonia to see if the modules improved understanding and reduced missed appoin…

This study tested whether cannabidiol (CBD) can reduce symptoms of social anxiety disorder. Sixty adults with moderate to severe social anxiety took either a high dose of CBD, a lower dose, or a placebo pill twice daily for three weeks. Researchers measured changes in anxiety dur…

This study looked at whether doing strength exercises with the non-surgical leg right after meniscus repair or transplant can prevent muscle loss in the leg that is immobilized. 50 adults who had surgery were randomly assigned to either do these exercises or follow standard rehab…

This study tested whether adding levetiracetam (a seizure medication) to standard antipsychotic treatment could reduce persistent psychotic symptoms and protect the brain in people with early psychosis. 65 participants who had been ill for less than 5 years and still had symptoms…

This study looked at 30 healthy older adults to see if a small brain region called the locus coeruleus (LC) shows early signs of Alzheimer's disease. Researchers used brain scans, sleep tests, and spinal fluid samples to measure LC function, sleep quality, and attention. The goal…

This study tested whether a short-chain fatty acid (SCFA) supplement, taken by mouth, could change gut bacteria and immune responses in people with rheumatoid arthritis (RA) who did not get enough help from methotrexate. About 20 to 35 adults with RA took the supplement for one t…

This study compared text message reminders to standard phone call reminders for getting people to complete a home stool test (FIT) for colon cancer screening. Over 1,200 adults from NYU family health centers took part. The goal was to see if texting could increase the number of p…

This study followed over 15,000 adults in the U.S., both with and without COVID-19, to learn why some people develop Long COVID (also called PASC). Researchers collected health data and samples over time to identify risk factors and common symptoms. The goal was to better underst…

This study looked at whether poor deep sleep and race are linked to Alzheimer's risk in healthy older adults. Researchers tracked sleep patterns and brain scans in 210 African-American and white volunteers aged 60-75. The goal was to understand why African-Americans have higher r…

This study followed 544 older adults in committed relationships for three years to understand how dementia affects both partners' mental and emotional health. Participants completed questionnaires every six months about their mood, anxiety, and relationship quality. The goal was …

This study tested whether a computer model can help choose which electrodes in a cochlear implant should be active to improve speech understanding. Fourteen adult cochlear implant users tried model-recommended settings and standard settings. The goal was to see if the computer-gu…

This study looked at how a person's weight influences the levels of special molecules produced after taking aspirin. These molecules help the body naturally resolve inflammation. Researchers gave different aspirin doses to 103 adults aged 40-70 and measured changes in their blood…