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Aspirin's hidden power: does your weight matter?

NCT ID NCT04697719

Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how body weight changes the way aspirin triggers special molecules that help calm inflammation. Researchers gave 103 adults aged 40-70 either aspirin or a placebo and measured these molecules in their blood. The goal was to understand if weight affects aspirin's ability to produce these healing signals, which could lead to better dosing for different people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

103 people

The number who actually took part.

Started

Nov 2021

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Age between 40 and 70 years Exclusion Criteria: 1. Anti-platelet medication use in the past 7 days 2. Aspirin intolerance or allergy 3. Known bleeding or clotting disorder 4. Chronic inflammatory or connective tissue disease 5. Immunological deficiency 6. Diabetes mellitus 7. Prior gastric or bariatric surgery 8. Active smoking 9. Platelet count \<100,000 10. Use of omega-3 fatty acid supplementation 11. Use of drugs or supplements known to inhibit COX-1/COX-2/lipoxygenases 12. Corticosteroid use 13. Recent initiation or change in dose of statin therapy 14. Pregnancy

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Conditions

The condition(s) this trial relates to.

Body Weight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Body weight

Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.