Northwestern University

This early-phase study tests whether a low dose of oral minoxidil can help regrow hair in people who have permanent hair loss from chemotherapy. Fourteen adults who finished chemo at least six months ago will take the pill and be monitored for hair growth and quality of life over…

This study aimed to compare two treatment plans for men with low-volume metastatic prostate cancer that still responds to hormone therapy. One group would receive hormone therapy plus abiraterone, while the other would get those two drugs plus chemotherapy (docetaxel). The goal w…

This study looks at adults with advanced liver cancer who first receive a radioactive treatment called Therasphere. After that, they get either immunotherapy (atezolizumab + bevacizumab) or targeted drugs (lenvatinib or cabozantinib). The goal is to see which approach better dela…

This study tests three treatments in men with advanced prostate cancer that has stopped responding to hormone therapy and has specific DNA repair defects. Participants receive either abiraterone (a hormone blocker), olaparib (a targeted drug), or both together. The goal is to see…

This study tests a special toolkit designed to help people with type 2 diabetes who need to start using insulin after leaving the hospital. The toolkit provides guidance and support to manage blood sugar safely at home. Researchers will track blood sugar levels and any problems l…

This study tests whether lisinopril, a common blood pressure medication, can prevent liver damage from getting worse in people with non-alcoholic fatty liver disease (NAFLD). About 45 adults with advanced liver scarring will take lisinopril for a period, and researchers will meas…

This study tests whether giving a TNF-alpha antibody just before a lung transplant can prevent kidney damage that often happens after surgery. About 20 adults getting a lung transplant at Northwestern will take part. Researchers will check kidney function and other outcomes like …

This study is testing a smartphone app called TECH to help teens aged 14-18 who are involved with the court system reduce or stop using marijuana. The app provides a private online community where teens can support each other anonymously. Researchers will track how many days teen…

This study tests a drug called vudalimab in people with advanced anaplastic or hurthle cell thyroid cancer that has spread. The drug helps the immune system attack cancer cells and may slow tumor growth. About 54 participants will receive the treatment to see if tumors shrink.

This early-phase trial tests whether adding mycophenolate mofetil (a drug usually used to prevent organ rejection) to standard chemotherapy and radiation can help treat glioblastoma, an aggressive brain cancer. About 60 newly diagnosed patients will receive different doses to fin…

This study aimed to see if a special PET/MRI scan using a radioactive tracer (18F-DCFPyL) can better detect serious prostate cancer in men with high PSA levels (2 ng/mL or more) compared to standard MRI. The approach combines two imaging techniques to find aggressive tumors witho…

This study tests a simple, low-cost screening tool called ToolBoxDetect that helps doctors spot early signs of memory loss or dementia during regular checkups. Over 41,000 adults aged 65 and older from diverse primary care clinics will take a quick cognitive test, and researchers…

This study tests whether metformin, a safe diabetes drug, can lower the risk of lung cancer in overweight or obese former smokers at high risk. Researchers will check if metformin changes certain immune cells in the lungs that are linked to tumor growth. The goal is to see if thi…

This study tests whether atorvastatin, a widely used cholesterol medication, can lower the risk of colon cancer in people with long-standing ulcerative colitis who carry a specific genetic change (P53 mutation). About 42 participants will take either atorvastatin or a placebo for…

This early study tests a special microbubble bath (Thera-Clean) that uses no chemicals to clean skin, reduce itch, and help wounds heal. About 20 people aged 2 and older with eczema, psoriasis, or other skin diseases will take the baths at home for 8 weeks. The goal is to see if …

This study tests a voice-assisted program using Amazon Alexa to help older adults (65+) with depression and their caregivers. Participants use the program for goal setting, reminders, and other support over 12 weeks. Some participants also get a guide to help them use the program…

This study looks at which parts of a mobile health program—social support or mindfulness training—best help breast cancer survivors increase their physical activity. About 304 women who finished cancer treatment within the past 5 years will use a phone app and wear an activity tr…

This study uses a smartphone app to find the best ways to help adults with binge eating and obesity. About 300 people will use the app, which sends different tips and support at different times. The goal is to learn which strategies work best for each person and in what order to …

This study was designed to see if a noninvasive device that stimulates the vagus nerve (tcVNS) could help people wake up faster and clearer after anesthesia. It planned to enroll adults having lumbar spine surgery and measure their recovery time, delirium, and depression. However…

This study looks at whether a "Patient Navigation 2.0 Checklist" can help Chinese adults in Chicago get recommended cancer screenings and address social needs like housing or food. About 600 people from Chinatown-area zip codes are taking part. The goal is to see if this simple t…

This study looks at skin and blood samples from people with ichthyosis, a genetic condition causing dry, scaly skin. Researchers want to find specific markers (biomarkers) that can help explain the disease better. The goal is to gather knowledge that could lead to new treatments …

This study checks if a 6-month parent coaching program for families of deaf or hard-of-hearing toddlers (12-18 months old) leads to better language, reading, and social skills when the children reach elementary school. Researchers will compare 88 children who got the coaching to …

This study tests two new methods to help people with familial hypercholesterolemia (a genetic high cholesterol condition) get their family members screened. About 800 adults from Penn Medicine will be assigned to one of three groups: automated health system messages, a patient na…

This study looks at how well a team-based program for depression works in primary care clinics. About 778 adults with depression symptoms are taking part. Researchers are measuring how fast the program is put into practice, how many people use it, and whether it helps reduce depr…

This study looks at how electrical brain stimulation affects the brain during surgeries for epilepsy or brain tumors. Researchers want to understand why this technique helps find important areas for speech and movement. About 65 adults having brain surgery will do simple tasks li…