Cholesterol drug may block colon cancer in colitis patients
NCT ID NCT04767984
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 26 times
Summary
This study tests whether atorvastatin, a widely used cholesterol medication, can lower the risk of colon cancer in people with long-standing ulcerative colitis who carry a specific genetic change (P53 mutation). About 42 participants will take either atorvastatin or a placebo for a period, and researchers will measure changes in cancer-related markers from colonoscopy biopsies. The goal is to find a new way to prevent cancer in this high-risk group.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Northwestern University
Chicago, Illinois, 60611, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
Conditions
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