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New quick memory check could help detect dementia early in routine doctor visits

NCT ID NCT04852601

Diagnosis Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times

Summary

This large study is testing a simple, low-cost digital screening tool called ToolboxDetect to help primary care doctors identify early signs of cognitive decline or dementia in adults aged 65 and older. Over 41,000 participants from diverse backgrounds will take a short computer test during regular check-ups. The goal is to see if this easy-to-use tool can reliably detect memory or thinking problems and integrate results into electronic health records, potentially leading to earlier diagnosis and care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ToolboxDetect (a digital cognitive screening test)
What this could lead to
If successful, this could provide a simple, low-cost way for doctors to routinely check for early signs of cognitive decline or dementia during regular check-ups.
What could go wrong
This is an observational study, not a treatment trial. It tests a screening tool, so it cannot improve health directly. The tool may miss some cases or cause unnecessary worry.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

35,403 people

The number who actually took part.

Started

Aug 2022

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals aged 65 and older will be considered. 2. Adults who may or may not have cognitive impairments. 3. Practices affiliated with Northwestern Medicine and Access Community Health Network. Exclusion Criteria: 1\. Severe, uncorrectable vision or hearing impairment

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive dysfunction Dementia

Contacts and locations

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.