National Institute Of Environmental Health Sciences (niehs)

This study aimed to count how many healthy adults in central North Carolina developed antibodies to the COVID-19 virus over one year. Researchers enrolled 643 people aged 18 and older who did not have COVID-19 at the start. Participants gave blood samples five times and completed…

This study looked at what causes autoimmune diseases that affect muscles and connective tissues, like myositis. Researchers collected blood samples and health information from 719 people, including patients, their relatives, and healthy volunteers. The goal was to find genetic an…

This study looked at whether taking vitamin D supplements can change key hormones that control the menstrual cycle, which are important for fertility. 57 women aged 19-40 with regular cycles took either vitamin D or a placebo for about 3 months. Researchers measured hormone level…

This study looked at how diet and exercise changes affect hormones and menstrual cycles in healthy young women. 38 women ages 18-28 with regular periods followed special diets and exercise programs. Researchers measured hormone levels to understand what causes temporary loss of p…

This study looked at people with low or no GnRH, a hormone that controls puberty and fertility. Researchers measured hormone levels, did imaging scans, and tested smell and hearing to find new patterns and genes linked to the condition. The goal was to better understand these rar…

This study created a registry of biological and environmental samples from over 5,000 healthy adults. The samples—including blood, urine, saliva, and household dust—were used to develop and validate new laboratory tests and ensure quality control. No treatment or intervention was…

This study followed nearly 90,000 farmers and their spouses to confirm health changes they reported, such as asthma and Parkinson's disease. Researchers checked medical records and collected cheek swabs to verify diagnoses. The goal was to better understand how pesticides and oth…

This study looked at why some military personnel develop myositis, a rare disease where the immune system attacks muscles, causing weakness and pain. Researchers compared 37 people with and without myositis, using questionnaires and blood samples to find possible environmental tr…

This study looked at why Black professionals often have poorer sleep than their white coworkers. Researchers held focus groups with 263 Black and white adults who work full-time. They asked about work, sleep habits, and health to find patterns that might explain the differences.

This study tested how well surveys and devices measure chemical exposure from household and personal care products. Eleven healthy women aged 35-74 wore air monitors, collected urine, and recorded product use for 12 days. The goal was to improve methods for tracking everyday chem…

This study looked at how certain genes in blood cells respond to environmental exposures, which may help explain why some people develop inflammation, cancer, or heart problems. Researchers collected blood samples from 178 healthy volunteers aged 18 to 45. The goal was to underst…

This study looked at how certain genes might change the way lung cells (macrophages) work when exposed to environmental pollutants. Twenty healthy adults gave blood and lung cell samples through a procedure called bronchoscopy. The goal was to understand, not to treat, so no new …

This study explores how specific gene variations influence the health of blood vessels in 178 healthy adults. Participants had a single visit for blood tests, urine samples, and an ultrasound to measure blood flow after a short-acting medication. The goal is to better understand …

This study looked at how smoking changes immune cells and whether those changes make smokers more vulnerable to severe COVID-19. Researchers followed 132 healthy smokers and non-smokers aged 30-55 for up to 6 months, taking blood, saliva, and nasal swabs to track infections and i…

This study looked at whether a natural chemical called TGF-Beta, found in higher levels in asthmatic lungs, makes people with asthma more vulnerable to RSV, a common respiratory virus. Researchers collected lung cells from 113 healthy adults and mild asthmatics using a thin tube …

This study looked at families where one sibling has a rheumatic disease (like rheumatoid arthritis or lupus) and the other does not. Researchers compared their blood cells, genes, and environmental exposures to find clues about why one got sick. Over 1,000 people took part, inclu…

This study looked at how small changes in the COX-2 gene affect the balance of immune cells that can lead to allergies or asthma. Researchers collected blood and urine samples from 117 adults to analyze these gene variations. No treatments were given; the goal was simply to under…