National Institute Of Environmental Health Sciences (niehs)

This study created a registry of anonymous biological and environmental samples from over 5,000 adult volunteers. The purpose was to collect materials like blood, urine, saliva, and household dust to help scientists develop, test, and improve the accuracy of new laboratory tests …

This study aimed to understand why some military personnel develop myositis, a rare autoimmune disease that attacks muscles, while others do not. Researchers compared service members with myositis to healthy service members, looking for common environmental exposures during milit…

This study aimed to understand why Black professionals tend to get less and poorer quality sleep than their White counterparts, which contributes to health disparities. Researchers conducted focus groups with 263 employed Black and White adults in North Carolina and Washington, D…

This study aimed to understand how specific variations in certain genes affect how a person's blood cells respond to stress or damage. Researchers collected blood samples from 178 healthy volunteers and some people with HIV to analyze their cells in a lab. The goal was to gather …

This study is following up with tens of thousands of farmers and their spouses to better understand how long-term exposure to things like pesticides might affect health. Researchers are checking the accuracy of health problems participants have reported, such as asthma and Parkin…

This study aimed to test and improve methods for measuring people's exposure to chemicals found in common household and personal care products. Researchers enrolled 11 healthy women who used many products daily to collect detailed data. Over 12 days, they gathered air, dust, urin…

This study aimed to understand why people with asthma often get sicker from a common respiratory virus called RSV. Researchers collected lung cells from 113 adults, both with and without mild asthma, to test in a lab. The goal was to see if a specific body chemical, TGF-beta, mak…

This study aimed to understand why some people develop autoimmune rheumatic diseases like rheumatoid arthritis or lupus while their genetically similar siblings do not. Researchers enrolled over 1,000 participants, including sibling pairs where one was affected and one was health…

This study aimed to understand how many adults in North Carolina developed antibodies to the COVID-19 virus over time. Researchers followed 643 healthy adults for one year, drawing their blood five times to check for antibodies and having them complete weekly symptom surveys. The…

This study aimed to understand why some women temporarily stop having periods, a condition called functional hypothalamic amenorrhea. Researchers observed 38 healthy women aged 18-28 to see how controlled changes in their diet and exercise affected their menstrual cycles and horm…

This study aimed to understand if taking vitamin D supplements affects hormones related to menstrual cycles and ovulation. Researchers enrolled 57 women aged 19-40 with regular cycles. Women with low vitamin D levels received a high-dose weekly supplement for about 90 days, while…

This study aimed to understand why smokers might get sicker from COVID-19. Researchers followed 132 healthy adults, both smokers and non-smokers, for up to 6 months. They collected blood and other samples to compare immune system differences before and after a COVID-19 infection.

This study aimed to understand how specific genes affect how lung cells respond to environmental pollutants. Researchers collected lung and blood samples from 20 healthy adults to study cell function in a lab. The goal was to gather basic knowledge about the early steps that migh…

This study aimed to understand how specific variations in a gene called COX-2 might influence the development of certain immune cells linked to allergic inflammation and asthma. Researchers enrolled 117 adults from a registry to compare blood and urine samples from people with di…

This study aimed to understand how specific gene variations might affect blood vessel function, which is important for heart health. Researchers examined 178 healthy adults who carried certain gene patterns to see if these variations were linked to differences in how their blood …

This study aimed to discover what causes rare autoimmune diseases that attack muscles and connective tissues, like polymyositis and dermatomyositis. Researchers studied 719 people, including patients and their family members, to look for genetic clues and environmental triggers l…

This study aimed to understand a rare condition where the body doesn't produce enough of a key hormone (GnRH) needed to start puberty and support fertility. Researchers studied 111 teenagers and adults with this condition to map their hormone patterns and look for other related h…