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Asthma lung chemical linked to severe virus risk

NCT ID NCT01224691

First seen Oct 31, 2025 · Last updated May 19, 2026 · Updated 33 times

Summary

This study looked at whether a natural chemical called TGF-Beta, found in higher levels in asthmatic lungs, makes people with asthma more vulnerable to RSV, a common respiratory virus. Researchers collected lung cells from 113 healthy adults and mild asthmatics using a thin tube inserted into the lungs. The goal was to understand the role of TGF-Beta in asthma-related RSV susceptibility, which could guide future treatments.

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Contacts and locations

Locations

  • NIEHS Clinical Research Unit (CRU)

    Research Triangle Park, North Carolina, 27709, United States

Conditions

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