King's College London

This study looks at two ways to treat advanced gum disease that has reached the area where the roots of back teeth split. About 59 adults with severe periodontitis will receive either non-surgical cleaning or a surgical procedure. The goal is to see which approach helps the tooth…

This study tests a type of talking therapy called Balance ACT to see if it improves quality of life for people with long COVID. About 196 adults with long COVID symptoms lasting over 12 weeks will either get the therapy or a self-help leaflet. The main goal is to measure physical…

This study tests a thinking skills program called CIRCuiTS, adapted for people with multiple sclerosis (MS). Twenty-four adults with MS will either start the program right away or wait 13 weeks. The program includes up to 36 hours of therapist-led and independent sessions over 12…

This study tests a brief psychological program called Y-MIND for depressed teens aged 15-18 in Ghanaian senior high schools. School counselors deliver the program, and researchers check if it's practical and helpful. 60 teens will take part, with half receiving Y-MIND and half ge…

This pilot study tests a 6-session psychological program called Y-MIND for young people aged 15-24 with depression in Zimbabwe. Trained non-professional counselors deliver the sessions. The goal is to see if the program is practical and helpful, and to measure depression symptoms…

This study tests whether an iPhone app called Juniver can help reduce symptoms of eating disorders like anorexia, bulimia, and binge eating. About 300 people in the UK and US will use the app for 12 weeks, and researchers will compare their progress to those on a waiting list. Th…

This study tests a digital program called EMBody designed to help young people aged 16-25 who have finished cancer treatment. The program aims to teach helpful ways of thinking about the body to improve health and quality of life. About 105 participants will use the program and r…

This study tests whether a specially designed group yoga program is practical and helpful for adults with ADHD symptoms. Twenty participants will be randomly assigned to either yoga or general movement classes. Researchers will track how many people join, stay, and complete the p…

This study surveys 1,000 medical trainees (students, residents, fellows) who work on-call shifts. It asks about their sleep habits, knowledge of sleep health, and how shift work impacts their sleep quality and daily performance. The goal is to gather information, not to test a tr…

This study analyzes data from 10,000 people with obstructive sleep apnea to see if CPAP therapy affects blood pressure differently in those who are excessively sleepy versus those who are not. Researchers will compare office and 24-hour blood pressure readings between the two gro…

This study looks at how a single dose of psilocybin, the active ingredient in magic mushrooms, affects brain activity in people with functional neurological disorder (FND). Researchers will use brain scans to see if psilocybin can change a key brain network linked to FND. The stu…

This observational study follows 201 mothers and their children, now aged 6 to 8, to see if the mother's severe mental illness around childbirth affects the child's stress response and overall development. Researchers will measure the child's reaction to mild stress tests and ass…

This study looks at three digital tools (MyFood24, Nutritics-Libro, Intake24) to track what people eat before, during, and after taking weight-loss medications like Wegovy or Mounjaro. About 50 adults with obesity will try one of these tools and give feedback through surveys and …

This study looks at whether Advance Choice Documents (ACDs) — written plans made with a care team when a person is well — can reduce the number of times people are forced into psychiatric hospital. Researchers at King's College London are testing this with 374 participants across…

This study looks at blood samples from 46 people with treatment-resistant depression who took psilocybin in a previous trial. Researchers want to see if inflammation levels in the blood before and after treatment are linked to how well the depression improves. The goal is to bett…