King's College London

This study looks back at data from 10,000 people with obstructive sleep apnea to see if a common treatment (CPAP therapy) lowers blood pressure differently depending on whether the patient feels very sleepy during the day. Researchers want to know if sleepy patients get a bigger …

This study aims to find the best way to treat severe gum disease around back teeth (molars) to prevent tooth loss. It compares two approaches: non-surgical deep cleaning versus surgical procedures that reshape or rebuild bone. The trial will follow 59 patients for five years to s…

This study is testing whether 'Advance Choice Documents' can help people with serious mental illness avoid forced hospitalizations and get better care. These documents let people state their treatment preferences when they are well, so their wishes are known during a crisis. Rese…

This study is testing a new therapy called ADIE Therapy, which aims to help breast cancer survivors manage anxiety. The therapy uses simple exercises, like focusing on heartbeat sensations, to help people better understand their body's signals. Researchers want to see if this app…

This study is testing a digital program called EMBody, which uses short films and reflection activities, to see if it can improve quality of life and wellbeing in young people who have finished cancer treatment. The program, co-created with survivors and doctors, aims to help 16-…

This pilot study is testing whether a brief psychological counseling program, delivered by school staff, is a practical way to help reduce depression in high school students in Ghana. The program involves 60 students aged 15-18 who report symptoms of depression. Researchers will …

This study is testing whether a smartphone app called Juniver can help people manage symptoms of eating disorders like anorexia, bulimia, and binge eating. The app provides self-help lessons, interactive tools, and moderated peer support groups, all designed to help users cope wi…

This is a small pilot study to see if a new 6-session talk therapy program called Y-MIND is practical and acceptable for treating depression in young people aged 15-24 in Zimbabwe. The program is delivered by trained community counselors, not doctors. The main goal is to see if t…

This study is testing whether a psychological therapy called Balance Acceptance and Commitment Therapy (ACT) can improve quality of life for people with long COVID. Researchers are comparing the therapy against standard self-help information in 196 UK adults who have had COVID sy…

This study aims to find the best digital tool for tracking what people eat while they are taking new weight-loss medications like Wegovy. Researchers will test three different food-tracking apps with 50 patients who have obesity and are starting treatment. The goal is to see if t…

This study aims to understand if a mother's severe mental illness around childbirth, like postpartum psychosis, is linked to how her child handles stress and develops years later. Researchers are following up with about 200 families, checking children aged 6 to 8 years old. They …

This study is analyzing blood samples from a previous trial to understand how psilocybin (a compound in certain mushrooms) might work for treatment-resistant depression. Researchers are measuring inflammation markers in the blood to see if a person's level of inflammation before …

This is a survey to understand how on-call hospital shifts affect the sleep, knowledge, and work performance of medical trainees and staff. It involves 1,000 participants from around the world and takes about 30-40 minutes to complete. The goal is to gather information, not to te…