Study tracks kids of moms with postpartum psychosis to see how they develop
NCT ID NCT06162689
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This observational study follows 201 mothers who had severe mental illness after childbirth and their children, now aged 6 to 8. Researchers will measure the children's stress responses, cognitive development, and mental health. The goal is to understand how maternal mental health affects child development over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify children at higher risk for developmental issues due to maternal postpartum mental illness, guiding early support.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all families.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 201 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study comprised 2 groups: women at risk of postpartum psychosis during pregnancy (exposed group) and women with no current or past history of psychiatric disorders (unexposed group). Cases were women at risk of postpartum psychosis because of a DSM-IV diagnosis of bipolar disorder, schizoaffective disorder or previous postpartum psychosis and controls were women who did not have a current or past history of psychiatric disorders. Clinical assessments were undertaken in the second and third trimesters of pregnancy and, following delivery, assessments of mother and infant were undertaken at 6 days, 8 weeks and 12 months post-delivery (n=72). At this stage, participants were asked to provide written consent to be contacted in the future about the possibility of taking part in a follow-up study.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women who participated in the previous study (Risk factors of perinatal mental disorders: Stress, electrophysiological, and neuroimaging markers), who gave consent to be contacted again, together with their offspring, and the child's father/co-parent. Exclusion Criteria: * Women who participated in the previous study who refused consent to be contacted again.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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King's College London
London, SE5 8AF, United Kingdom