King's College London

This study is for people who have chest pain and shortness of breath but no blockages in their main heart arteries. The likely cause is a problem with the heart's tiny blood vessels, called coronary microvascular dysfunction (CMD). The study will test ways to treat CMD by looking…

This study tests a therapy program called the Cannabis Clinic for Psychosis (CCP) to help people with first-episode psychosis reduce or stop cannabis use. About 80 adults under early psychosis care who want to cut down will either get the CCP therapy right away or wait and receiv…

This study compares a new, minimally invasive non-surgical treatment (MINST) to the standard cleaning method for peri-implantitis, an infection around dental implants. About 80 adults with infected implants will be randomly assigned to one of the two treatments. The goal is to se…

This study tests whether a short virtual reality (VR) program is safe and acceptable for adults with anorexia nervosa. Participants will do five 20-30 minute VR sessions over one week while continuing their usual care. The study focuses on whether people find the VR helpful and i…

This study looks at how continuous positive airway pressure (CPAP) therapy affects the complexity of body signals like oxygen levels, heart rate, and airflow in adults with obstructive sleep apnea. Researchers will analyze data from 160 people who already completed a trial on 3D-…

This study looks at why some people improve more than others after anxiety treatment. Over 4,400 adults with elevated anxiety will use a digital brain training program called LENS, which helps change negative thinking patterns. Researchers will combine genetic data and questionna…

This study talks to children with life-limiting illnesses, their families, and professionals to understand what 'complexity' really means in their care. The goal is to create a shared definition that can help improve how health, education, and social services work together. About…

This study looks at whether taking cannabidiol (CBD) changes how much THC heavy cannabis users need to feel intoxicated. About 30 adults who use cannabis heavily will take part. They will receive either CBD or a placebo, then inhale THC using a vaporiser and decide when they've h…

This study aims to understand what helps people stay healthy as they get older. It will enroll 100,000 people aged 12 and up across the UK. Participants use smartphones or computers from home and may provide samples like blood or saliva. The goal is to learn how lifestyle, enviro…

This study looks at whether eating more fiber can change body measures linked to early-onset bowel cancer. About 200 adults in the UK will follow either the standard UK healthy diet (30g fiber/day) or a higher-fiber version (40g/day) for 12 weeks. Researchers will compare stool, …

This study will test a new, gentle device that collects fluid from the skin of babies up to 6 months old. Researchers want to see if the device is comfortable and can measure chemical signals that may help explain why some babies develop eczema. The goal is to find early clues th…

This study aims to understand how maternity clinicians (midwives and obstetricians) make decisions about medical interventions during childbirth. Researchers will observe and interview 200 clinicians to learn the reasons behind their choices. The goal is to gather insights that c…

This study aims to improve HIV outpatient care by routinely asking patients about their mental health, symptoms, and quality of life through a questionnaire called POSITIVE OUTCOMES. About 17,000 adults with HIV at five clinics in the UK and US will take part. Researchers will wo…