Irccs San Raffaele

This study compares two medical tools used during surgery to break up and remove kidney stones. Researchers want to see if a newer tool with built-in suction helps remove stones more completely and reduces infections after surgery compared to the standard tool. About 134 adults w…

This study is testing a highly precise form of radiation therapy for people with kidney cancer who are not good candidates for surgery. The main goal is to see if this targeted approach can effectively control the cancer while causing fewer side effects. It will involve 60 partic…

This study aims to see if a new type of wide-field eye scanner (OCTA) can help doctors better diagnose and monitor a range of eye diseases. It will involve 200 participants, some with conditions like macular degeneration or diabetic retinopathy and some healthy controls. Research…

This study aims to see if a new AI-assisted device is better than the standard finger exam at finding hidden tears in the anal muscles after a woman's first vaginal birth. Researchers will test both methods on 110 first-time mothers shortly after delivery. An ultrasound scan done…

This study aims to see if a modified ultrasound method can accurately measure disease activity and severity in people with moderate-to-severe ulcerative colitis. Researchers will follow 25 patients starting a new medication for 24 weeks, comparing ultrasound results to the curren…

This study tests whether artificial intelligence (AI) can create one type of brain scan image from another, using existing patient data. Currently, diagnosing Alzheimer's often requires two separate scans. If successful, this AI method could reduce radiation exposure, costs, and …

This study is testing whether a vaginal electrical stimulation device called VTone can help women with stress urinary incontinence. Fifteen women will receive eight weekly treatments, then be followed for three months to see if their leaks decrease and quality of life improves. T…

This study is testing whether a gentle, low-heat radiofrequency treatment delivered through the vagina can help control overactive bladder symptoms. The treatment aims to calm overactive nerves in the bladder wall without damaging surrounding tissues. Researchers will enroll 48 w…

This study aims to improve the diagnosis of a rare and aggressive eye cancer called vitreoretinal lymphoma. Researchers will use blood samples from healthy donors to test four different combinations of settings on a standard eye surgery machine. The goal is to find which settings…

This study aims to understand if teens with celiac disease are more likely to develop unhealthy eating behaviors compared to their peers. Researchers will give questionnaires to 300 teens, some with celiac disease and some without, to compare their eating habits and concerns. A s…

This study aims to improve the understanding of stroke by analyzing how different patterns seen on brain scans (like MRI or CT) relate to the symptoms patients experience. Researchers will collect and review medical records and brain scans from over 1,100 adults who have had a sc…

This study aims to better understand and detect a condition called acute sarcopenia, which is a rapid loss of muscle mass and strength that can happen to older adults during a hospital stay. Researchers will follow 280 patients aged 65 and older, using simple strength tests and a…

This study will create a long-term health registry tracking 10,000 adults with diabetes and related metabolic conditions like high blood pressure and liver disease. Researchers will collect routine medical information over at least 10 years to identify patterns that could improve…

This study aims to track how well endoscopic ultrasound biopsies diagnose pancreatic and bile duct cancers in real-world hospital settings. It will follow 2,500 patients across specialized pancreas centers in Italy's Lombardy region to measure diagnostic accuracy, safety, and how…

This study aims to better understand walking problems by comparing how people with gait disorders walk versus healthy people. Researchers will use small wearable sensors placed on the body to measure joint movement and muscle activity during walking. The goal is to gather detaile…

This study aims to develop better ways to monitor Alzheimer's treatment using MRI scans instead of current PET scans. Researchers will follow 50 people with early Alzheimer's who are receiving standard antibody treatments to see if MRI can predict when treatment has worked enough…

This study aims to learn more about the side effects that can occur when cancer patients receive immunotherapy drugs. It will follow 500 adult patients with various cancers to track when these side effects happen, how severe they are, and how they are managed. The goal is to gath…

This study aims to measure how much of the antibiotic delafloxacin gets into the blood and different tissues of patients with serious skin, bone, or joint infections. Researchers will enroll 20 adult patients already receiving this antibiotic treatment and collect blood samples a…

This study looks back at medical records and eye scans from up to 200 people with inherited retinal diseases, which cause progressive vision loss. Researchers aim to understand how these diseases naturally change over time and how a person's specific genetic cause relates to thei…

This study aims to see if combining two types of scans (PET and MRI) can more accurately diagnose brain tumors and tell if treatment is working. It will observe 270 adults with brain tumors, using only scans and tests that are part of their normal care. The goal is to gather bett…

This study aims to understand if taking a tiny cell sample from an embryo during IVF genetic testing affects a child's growth during their first year. Researchers will compare the growth of 330 children born after this procedure to children born from standard IVF cycles. The stud…