Irccs San Raffaele
Clinical trials sponsored by Irccs San Raffaele, explained in plain language.
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New drug shows promise for Tough-to-Treat bladder cancer before surgery
Disease control CompletedThis study tested a drug called sacituzumab govitecan given before bladder removal surgery in 44 people with muscle-invasive bladder cancer who could not take or refused standard cisplatin chemotherapy. The goal was to see if the drug could completely eliminate the tumor by the t…
Phase: PHASE2 • Sponsor: IRCCS San Raffaele • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Prostate fluid particles may unlock earlier cancer detection
Diagnosis CompletedThis study looked at tiny particles called extracellular vesicles found in prostate fluid from 100 men. The goal was to find unique molecular patterns that could help tell aggressive prostate cancer from less serious forms. Researchers hope this approach will lead to more accurat…
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated May 20, 2026 11:53 UTC
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Heart MRI study reveals surprising frequency of valve quirk
Knowledge-focused CompletedThis study reviewed heart MRI scans from 4000 adults to find out how often a small variation in the heart valve, called mitral annular disjunction (MAD), occurs. The goal was to see if MAD is linked to heart rhythm problems or valve issues. The research was purely observational a…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:58 UTC
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AI matches radiologists in prostate cancer detection study
Knowledge-focused CompletedThis study tested an AI software called Quantib Prostate to see if it could find suspicious prostate cancer spots on MRI scans as accurately as expert radiologists. Researchers looked back at 200 men who had prostate MRIs and biopsies. The goal was to compare the AI's performance…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:55 UTC
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New endoscopic technique may help detect pancreatic cancer cells earlier
Knowledge-focused CompletedThis study tested whether it is safe and possible to collect a small blood sample from the portal vein (a major liver blood vessel) during a routine endoscopic ultrasound in 23 people with pancreatic cancer. The goal was to find and count circulating tumor cells (cancer cells tha…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:53 UTC
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AI could predict heart attacks before they happen
Knowledge-focused CompletedThis study looked at 3000 patients with suspected coronary artery disease to see if artificial intelligence could better predict who is at risk for heart attacks or death. Researchers used heart scan images and patient health data to build a risk model. The goal is to help doctor…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:52 UTC
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AI reads heart scans to spot hidden danger
Knowledge-focused CompletedThis study looked at 2190 people with coronary artery disease who had a CT scan. Researchers used artificial intelligence to find hidden signs of risk that doctors might miss. The goal was to create a score that helps predict who might have a heart attack or need urgent care, so …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:52 UTC
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Massive study probes cancer risk in EoE patients
Knowledge-focused CompletedThis study looked at health records of 100,000 people to find out if those with eosinophilic esophagitis (EoE) are more likely to develop esophageal cancer. Researchers wanted to see if any increased risk is due to EoE itself or other common conditions like GERD or Barrett's esop…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:48 UTC
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Thinking about right and wrong: can we train our moral compass?
Knowledge-focused CompletedThis study looked at whether a short lesson on moral reasoning could help people give better reasons for their moral decisions. 86 healthy university students took part. They were split into two groups: one received a moral reasoning lesson, the other a non-moral lesson. Their ab…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Microscope clues could change how we treat ulcerative colitis
Knowledge-focused CompletedThis study looked back at 159 people with ulcerative colitis who started a new advanced treatment. Researchers wanted to see if checking tissue samples under a microscope (histology) could predict who would later need stronger treatment, a hospital stay, or surgery. They compared…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 02:45 UTC
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New study tests safer methods to remove glue after braces
Knowledge-focused CompletedThis study looked at 142 people who had braces or clear aligners removed. It compared two gentle cleaning methods to remove leftover glue from teeth: one using a special ultrasonic tool and another using a polishing bur. The goal was to see which method is safer for tooth enamel …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Prostate cancer mystery: why do two top scans disagree?
Knowledge-focused CompletedThis study looked at 30 men with prostate cancer to understand why MRI and PSMA PET scans sometimes detect different tumors. Researchers analyzed stored tissue samples to see if these mismatched spots are harmless, aggressive, or a different type of cancer. The goal is to help do…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Smoking's immediate impact on eye blood vessels revealed
Knowledge-focused CompletedThis study looked at how smoking changes the blood vessels in the retina, the light-sensitive tissue at the back of the eye. Forty healthy adults took part: 20 who smoked regularly and 20 who did not. Researchers used special eye scans to measure blood vessel size and function be…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Gene score may predict prostate cancer worsening
Knowledge-focused CompletedThis study looked at 185 men with low-risk prostate cancer who chose active surveillance (monitoring instead of immediate treatment). Researchers used a genetic risk score based on common DNA variants to see if it could predict when the cancer might progress. The goal is to help …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Vitamin D3 may lower long COVID risk, new study suggests
Knowledge-focused CompletedThis study reviewed medical records of 200 adults from an endocrinology clinic to see if taking vitamin D3 supplements lowered their chances of developing Long COVID after a COVID-19 infection or getting COVID-19 after vaccination. Researchers compared patients who took vitamin D…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC