Irccs San Raffaele

This study reviews medical records of 36 adults with a rare and aggressive brain lymphoma (PCNSL) that has come back or not responded to prior treatment. Researchers want to see how well the targeted drug ibrutinib works, either alone or combined with standard chemotherapy (R-CHO…

This study aimed to see if giving the immunotherapy drug pembrolizumab before radical prostatectomy could reduce lymph node invasion in high-risk prostate cancer patients. It was designed for men scheduled for prostate removal and lymph node dissection. However, the study was wit…

This study looks at whether people with HIV can get their long-acting injections at home instead of at the hospital. About 120 adults who are already stable on HIV medication will be randomly assigned to receive injections either at home or in the hospital. The goal is to see whi…

This study aims to understand how kidney tumors differ from one another in people with von Hippel-Lindau (VHL) syndrome, a rare genetic condition. Researchers will use advanced imaging, multiple tumor biopsies, and lab-grown tumor models to map these differences. The goal is to l…

This study aims to create a questionnaire that measures how patients feel during endoscopic ultrasound, a procedure used to examine the pancreas and bile ducts. Researchers will ask 171 patients and healthcare workers to rank what matters most during the procedure. The goal is to…

This study looks at whether a special type of scan (PET/MRI) can predict how well esophageal cancer responds to chemotherapy and radiation given before surgery. Researchers will compare scan results with tissue samples after surgery to see if the scans can tell who is responding …

This study uses advanced brain scans to track how diseases like frontotemporal dementia, ALS, and related conditions spread through the brain's network. Researchers will follow 645 participants, including patients and healthy volunteers, for up to 2 years. The goal is to create m…

This study examines how often a specific DNA repair issue (HRD) occurs in people with a certain type of advanced lung cancer (EGFR-mutated NSCLC). Researchers will analyze tumor samples from 100 participants to see if this issue is linked to how the cancer behaves. The goal is to…

This study looks at two new, faster methods for thawing frozen eggs and compares them to the usual slow method. Researchers will check how many eggs survive and how healthy their internal structures are. The goal is to find the best way to warm eggs for future fertility treatment…

This study is a registry that collects information from 200 patients who had a tear in the wall of the aorta (aortic dissection) and were treated with a procedure called STABILISE. The goal is to see how well the procedure works and what complications may occur. The study does no…

This study uses machine learning to analyze data from 5,000 IVF patients to find patterns that predict pregnancy success. Researchers hope the model will help doctors personalize treatments, improving success rates and reducing emotional and financial stress. The study is not tes…

This study looks at whether virtual reality training before Gamma Knife brain surgery can improve pain relief for people with trigeminal neuralgia, a severe facial pain condition. Researchers will also use MRI scans and artificial intelligence to find brain patterns that predict …

This study is creating a large collection of biological samples and health data from 3,000 people. The goal is to help researchers better understand gynecological disorders, male and female infertility, and pregnancy-related conditions. Participants provide samples and informatio…