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Lung cancer clue: could a DNA glitch guide future treatments?

NCT ID NCT07303218

First seen Jan 04, 2026 · Last updated Apr 30, 2026 · Updated 18 times

Summary

This study examines whether a specific DNA repair problem, called homologous recombination deficiency (HRD), is common in a certain type of advanced lung cancer (EGFR-mutated NSCLC). Researchers will analyze tumor samples from 100 patients to see if HRD is linked to how the cancer behaves or responds to treatment. The goal is to better understand this cancer subgroup and explore whether they might benefit from PARP inhibitor drugs in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dept. Medical Oncology

    Milan, MI, 20132, Italy

Conditions

Explore the condition pages connected to this study.