EGFR
Clinical trials for EGFR explained in plain language.
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New hope for lung cancer patients when standard pills fail
Disease control Recruiting nowThis study tests a two-step treatment for people with advanced non-small cell lung cancer whose current targeted therapy (a third-generation EGFR TKI) has stopped working. Participants first receive chemotherapy (pemetrexed plus platinum) followed by a newer targeted drug called …
Matched conditions: EGFR
Phase: PHASE2 • Sponsor: Betta Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 08:37 UTC
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New pill shows promise against tough lung cancer mutations in phase 3 trial
Disease control Recruiting nowThis study tests a new daily pill, firmonertinib, against standard chemotherapy for people with advanced non-small cell lung cancer that has certain EGFR mutations (PACC or L861Q). About 300 participants will be randomly assigned to receive either the pill or chemo. The goal is t…
Matched conditions: EGFR
Phase: PHASE3 • Sponsor: Allist Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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New hope for Hard-to-Treat cancers: first human trial of VIR-5525 begins
Disease control Recruiting nowThis early-phase study tests a new drug called VIR-5525, alone or with an immunotherapy (pembrolizumab), in adults with advanced solid tumors that have a protein called EGFR. The main goals are to check safety and find the right dose. Up to 450 participants will be enrolled acros…
Matched conditions: EGFR
Phase: PHASE1 • Sponsor: Vir Biotechnology, Inc. • Aim: Disease control
Last updated May 26, 2026 08:20 UTC
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New drug EPI-326 enters first human tests for tough cancers
Disease control Recruiting nowThis early-phase study tests a new drug called EPI-326 in about 110 people with advanced lung cancer (with a specific EGFR gene change) or head/neck cancer. The main goal is to check safety and find the best dose. Participants receive the drug and are monitored for side effects a…
Matched conditions: EGFR
Phase: PHASE1 • Sponsor: EpiBiologics • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Salt swap after kidney surgery: a simple diet change to save kidneys?
Disease control Recruiting nowThis study looks at whether using a salt substitute instead of regular salt can help protect kidney function in people who have had surgery for a kidney tumor. About 200 adults will be randomly assigned to use either a salt substitute or regular salt for one year. Researchers wil…
Matched conditions: EGFR
Phase: NA • Sponsor: Jinling Hospital, China • Aim: Disease control
Last updated May 19, 2026 12:00 UTC