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EGFR
Clinical trials for EGFR explained in plain language.
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Can a Triple-Drug combo before surgery eliminate EGFR-Mutant lung cancer?
Cure Not yet recruitingThis phase II trial tests whether giving a combination of firmonertinib, anlotinib, and chemotherapy before surgery can shrink or eliminate tumors in people with resectable EGFR-mutant non-small cell lung cancer. The study enrolls adults with stage IIA-IIIB disease who have speci…
Matched conditions: EGFR
Phase 2 • Sponsor: Hubei Cancer Hospital • Aim: Cure
Last updated Sep 10, 2026 00:00 UTC
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Can a targeted pill clear hidden lung cancer cells after surgery?
Disease control Not yet recruitingThis phase 2 trial tests whether zipalertinib, an oral drug that targets cancer cells with atypical EGFR mutations, can eliminate remaining cancer cells in people with early-stage non-small cell lung cancer. Participants who have completed standard treatment and show signs of min…
Matched conditions: EGFR
Phase 2 • Sponsor: Stanford University • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Can removing the main tumor boost targeted therapy in advanced lung cancer?
Disease control Not yet recruitingThis study looks at whether surgically removing the primary lung tumor before starting the targeted drug osimertinib can help people with advanced EGFR-mutant non-small cell lung cancer. About 118 patients with stage III-IV cancer will be randomly assigned to get surgery plus osi…
Matched conditions: EGFR
Phase 2 • Sponsor: Jianxing He • Aim: Disease control
Last updated Jun 26, 2026 18:21 UTC