EGFR
Clinical trials for EGFR explained in plain language.
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New hope for hard-to-treat cancers: experimental drug enters human testing
Disease control OngoingThis early-stage study tests a new drug called TT125-802 in about 50 adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety and find the best dose. Researchers will also watch for any tumor shrinkage an…
Matched conditions: EGFR
Phase: PHASE1 • Sponsor: TOLREMO therapeutics AG • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New pill after lung cancer surgery aims to keep cancer from coming back
Disease control OngoingThis study tests whether adding the drug zipalertinib to standard chemotherapy after lung cancer surgery helps prevent the cancer from returning. It includes 360 adults with early-stage lung cancer (stage IB-IIIA) that has certain uncommon EGFR gene mutations. Participants will r…
Matched conditions: EGFR
Phase: PHASE3 • Sponsor: Taiho Oncology, Inc. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Lung cancer clue: could a DNA glitch open door to new treatments?
Knowledge-focused OngoingThis study examines how often a specific DNA repair issue (HRD) occurs in people with a certain type of advanced lung cancer (EGFR-mutated NSCLC). Researchers will analyze tumor samples from 100 participants to see if this issue is linked to how the cancer behaves. The goal is to…
Matched conditions: EGFR
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 26, 2026 09:15 UTC
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Smartphone app and fitbit join forces to monitor lung cancer treatment side effects
Knowledge-focused OngoingThis study involves 30 lung cancer patients taking oral targeted therapy. They will use a smartphone app, a Fitbit, and a smart pill cap to track symptoms and medication use for up to 24 weeks. The goal is to see if this remote monitoring system is practical and can help improve …
Matched conditions: EGFR
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC