Indiana University

This study looks at whether a supervised ketogenic diet is safe and effective for weight loss in 40 obese adults with NASH cirrhosis, a serious liver condition. Participants are randomly assigned to either the keto diet or standard dietary advice for 16 weeks. The main goals are …

This study tests a program called PATH4YOU that helps women ages 18-49 get birth control counseling and same-day access to low-cost contraception. The goal is to reduce unintended pregnancies and improve health equity. Researchers will work with clinics in Indiana to provide preg…

This study tests a robotic device (G-EO System) that helps people with Parkinson's disease practice walking. The goal is to see if it is safe and can improve mobility, function, and quality of life. About 30 adults with mild to moderate Parkinson's will take part. The study compa…

This study is tracking how well a non-surgical procedure called POEM works for people with achalasia, a condition that makes it hard to swallow. POEM uses an endoscope to cut the tight muscle at the bottom of the esophagus without any cuts on the body. The goal is to improve symp…

This study tests whether a simple, self-administered acupressure routine can reduce pain for people with sickle cell disease. Researchers will enroll 300 adults who have chronic pain or recent pain crises. Participants will apply acupressure to themselves every other day and repo…

This study collects blood samples from 19 adults with metastatic melanoma or kidney cancer that shrank without treatment. Researchers want to study the immune system's role in this rare event. Participants give blood and share medical history, but no treatment is given. The goal …

This study gathers information from 500 people who had a TIF procedure—a no-incision surgery for acid reflux—at Indiana University. Researchers will track changes in quality of life and reflux symptoms using questionnaires. The goal is to understand how well the procedure works i…

This study tests whether showing parents an infographic about obstructive sleep apnea (OSA) symptoms helps identify more children with the condition. About 200 parents of children with OSA symptoms will either see the infographic before a doctor visit or receive usual care. Resea…

This study compares two methods for removing medium-to-large colon polyps during a colonoscopy: cutting the polyp into pieces (CSPR) versus lifting and removing it in one piece (Cold EMR). Both methods use a cold wire snare, avoiding heat. The goal is to see which technique remov…

This study tests whether a mild, non-invasive brain stimulation technique called tDCS can help healthy adults learn a virtual reality rhythm game (Beat Saber) more quickly. Fifty-two participants will play the game while receiving either real or fake stimulation to see if the bra…

This study looks at how opioid use disorder (OUD) and medication-assisted therapy affect the brains of pregnant women. Researchers will compare brain scans of 40 pregnant women with OUD to those without. The goal is to learn how the body processes medication during pregnancy and …

This study tests whether an AI-powered tool that uses electronic medical records can help predict and reduce delirium (sudden confusion) in adults aged 65 and older after major surgery. About 60 participants will be randomly assigned to receive a paper or electronic alert about t…

This study tests whether mild electrical stimulation on the outer ear can activate the vagus nerve, which controls stomach function. Researchers will measure nerve activity in 30 healthy adults using skin electrodes. The goal is to learn how to study this nerve better, which may …

This study was designed to compare two ways of giving oxygen to high-risk patients during colonoscopy sedation: a standard nasal cannula and a special mask that provides positive airway pressure. The goal was to see which method better prevents drops in oxygen levels. However, th…

This study looks at how common kidney injury is in newborns in intensive care, and what factors increase the risk. Researchers will review medical records from thousands of babies across many countries. The goal is to improve detection and long-term kidney health for these vulner…

This study looks at whether making changes at the health system level can help more people with end-stage kidney disease start the process of getting a kidney transplant. Researchers will work with five large transplant centers and about 800 dialysis centers to see if these chang…

This study explores whether stimulating a nerve in the outer ear can reach the internal vagus nerve, which controls stomach function. Researchers hope this approach could lead to new treatments for nausea, vomiting, and stomach disorders. The study involves 131 healthy volunteers…

This study looks at how a stomach pacemaker (gastric electrical stimulation) helps people with gastroparesis, a condition where the stomach empties too slowly. Researchers will place a flexible, non-invasive electrode patch on the neck to measure nerve signals from the vagus nerv…

This study looks at how a stomach pacemaker (gastric electrical stimulation) affects the vagus nerve and heart rate in 300 people with gastroparesis, a condition where the stomach empties slowly. Researchers measure nerve signals and hormone levels when the device is on and off. …

This study looks at why some babies born early have breathing issues in their first year. Researchers will measure lung function in 249 infants to find patterns that predict future problems. The goal is to better understand and identify risks, not to test a new treatment.

This study is testing a new tool called PATH that helps doctors check for age-related health problems in people with HIV who are 50 or older. The goal is to see if the tool is easy to use and helpful for both patients and doctors. About 60 participants from two HIV clinics will t…