Huashan Hospital

This early-stage study tests a new drug called YSCH-01, alone or with another drug (atezolizumab), in 10 people whose glioblastoma (a severe brain cancer) has returned. The main goal is to check safety and see if the treatment helps patients live at least one year longer. Partici…

This study tests whether SGLT2 inhibitors, a type of diabetes drug, can improve the heart's upper chamber function in people with intermittent atrial fibrillation, high blood pressure, and abnormal blood sugar. The goal is to prevent heart failure. About 66 adults will receive ei…

This study tests if people with tuberculosis (TB) but no symptoms can be treated with a shorter course of medication—17 weeks instead of the usual longer regimen. Researchers will compare the success rates and relapse rates between the shorter and standard treatments. The trial i…

This study tests a clot-busting drug called tenecteplase in Chinese stroke patients who arrive at the hospital more than 4.5 hours after symptoms start. About 890 participants will receive either the drug or standard care to see if it helps them recover without disability. The go…

This study tests a new, non-invasive brain stimulation method called temporal interference stimulation to see if it can safely help people with severe consciousness disorders, like a coma or vegetative state, regain awareness. The trial will involve 20 adults aged 18-75 who have …

This study tests whether placing probiotics into the unused part of the intestine before stoma reversal surgery can improve bowel function in people treated for ultra-low rectal cancer. About 156 adults who had a temporary ileostomy will be randomly assigned to receive probiotics…

This study tests whether lying flat after surgery for chronic subdural hematoma (a brain bleed) can prevent it from returning. About 830 adults aged 60 and older will be randomly assigned to either lie flat or follow standard care. The goal is to see if this simple body position …

This study compares a newer targeted drug, obinutuzumab, with a standard chemotherapy-based treatment (cyclophosphamide plus steroids) for people with a serious kidney condition called primary membranous nephropathy. About 144 adults with high protein in their urine will receive …

This study aims to find the best way to diagnose MOG antibody disease, a rare autoimmune condition that affects the brain and nerves. Researchers will compare two lab tests (live-cell and fixed-cell) in 240 adults suspected of having the disease. The goal is to see which test is …

This study tests whether a 1-month, ultra-short TB prevention regimen works as well as the standard 3-month treatment for school students and staff who have been in close contact with someone with active TB. About 3,520 participants aged 13 and older will be enrolled. If successf…

This study looks at whether miniature, lab-grown versions of a patient's tumor (called organoids) can accurately predict which cancer drugs will work best. Researchers will compare the organoid test results with how the patient actually responds to treatment. The goal is to see i…

This study follows 33,000 adults with chronic hepatitis B to see how different antiviral treatments affect their health over 5 years. Researchers will compare drugs like entecavir and tenofovir, alone or with peginterferon, to find which best lowers liver cancer risk and helps cl…

This study is for people with recurrent or metastatic salivary gland cancer. Researchers want to see if a lab test using your own tumor cells (called an organoid) can predict which drug will work best for you. The study will compare the lab test results with how you actually resp…

This study aims to collect information from 100,000 people with Parkinsonian disorders in China over 10 years. Participants will fill out online questionnaires about their health, mood, sleep, and quality of life every 3 months. The goal is to better understand how the disease pr…