Huashan Hospital

This study tests whether adding the targeted drug orelabrutinib to standard chemotherapy can improve outcomes for people newly diagnosed with primary central nervous system lymphoma (PCNSL), a rare brain cancer. About 215 adults will be randomly assigned to one of three treatment…

This early-phase study is testing a new treatment called C-CAR168 for people with severe autoimmune diseases affecting the brain and spinal cord, such as multiple sclerosis and autoimmune encephalitis, that have not improved with standard therapies. The treatment uses a patient's…

This study looks at how things like air pollution, noise, and lack of green spaces in cities may affect mental health. Researchers will track 680 people with depression, anxiety, or alcohol use disorder, plus healthy volunteers, using wearable devices and a smartphone app. The go…

This study looks at whether a special PET scan (18F-AGX) can detect early changes in brain tumors (low-grade IDH-mutant gliomas) during treatment with the drug Vorasidenib. Ten adults with recurrent or residual tumors will receive the drug and undergo both MRI and PET scans over …