Hospital For Special Surgery, New York

This study is testing whether a common bone-strengthening drug (bisphosphonate) can slow down hearing loss in people with Osteogenesis Imperfecta (OI), also known as brittle bone disease. It will follow 100 adults and children with OI for about 5 years to see if the drug helps pr…

This study is testing if injecting a concentrated form of a patient's own bone marrow during a second ACL knee surgery can help control pain and prevent long-term arthritis. Researchers will compare patients who receive the injection to those who get a placebo procedure. They wil…

This early-stage study is testing a new oral drug called ONTO1 for people with lupus, including a serious kidney complication called lupus nephritis. The main goal is to find the highest safe dose and see if it helps improve symptoms when taken alongside standard lupus medication…

This study is testing if adding a patient's own bone marrow to a standard knee surgery leads to better recovery. 50 adults with knee cartilage or meniscus damage will be randomly assigned to get either the bone marrow injection or a placebo saltwater injection during their proced…

This study is testing a new medical device called the BrightPoint Epidural device. The device uses light technology to help doctors more accurately find the correct space in the spine when placing an epidural needle for pain management during lumbar spine surgery. Researchers wan…

This study is testing a new type of back brace worn after major spinal surgery. The goal is to see if the brace can prevent a common problem where the spine above the surgical area begins to curve forward. Researchers will compare the new brace to standard care in 84 adults havin…

This study is testing if an injection of platelet-rich plasma (PRP), made from a patient's own blood, can help prevent arthritis from developing after a serious knee ligament (ACL) tear. Researchers are recruiting 56 people with recent ACL injuries to receive either the PRP injec…

This study is testing two different methods for managing pain after total knee replacement surgery. Researchers want to see if using a small, temporary catheter that continuously delivers numbing medicine to the leg for about two days works better than a standard single injection…

This study is testing whether a specific nerve block given during minimally invasive lower back surgery can help patients use fewer opioid pain medications after their operation. Researchers will compare two groups: one receiving the nerve block and one receiving standard care. T…

This study is comparing two different ways to manage pain after knee replacement surgery. Researchers want to see if using a continuous pain medication catheter works better than a single injection at reducing opioid painkiller use. The study involves 94 patients aged 18-65 who a…

This study is testing a new locked device designed to help patients use opioid pain medications more safely after spine surgery. Thirty patients having a common back operation will be split into two groups: one gets the new smart dispenser that unlocks only at scheduled times via…

This study is testing whether injections of platelet-rich plasma (PRP) can help reduce pain and improve function in people with shoulder arthritis. Researchers are comparing two different strengths of PRP injections against a simple saline injection to see which works best. The t…

This study is testing if applying a steroid directly to the spine during a common back surgery helps patients recover better. Researchers will compare patients who get the steroid to those who get a placebo to see if it reduces pain, shortens hospital stays, helps people return t…

This small pilot study is testing whether a new robotic knee brace can help children with cerebral palsy walk better. Ten children with a crouched walking style will try the device during supervised sessions. Researchers will measure if the brace helps them walk more upright, tak…

This study is testing a new, FDA-approved non-opioid pain medication called Suzetrigine (Journavx™) for people having hip replacement surgery. The goal is to see if it can effectively manage post-surgery pain and reduce the need for traditional opioid painkillers, which can have …

This study is comparing two different nerve block techniques used to manage pain after knee surgery in children and teenagers. Researchers want to see which method—an anterior femoral cutaneous nerve block or an adductor canal block—leads to better pain control, less need for opi…

This study aims to understand why some people experience repeat knee dislocations after a common ligament repair surgery. Researchers will follow 850 patients aged 10-35 for two years after their surgery, collecting survey data about their knee function and stability. The goal is…

This study follows golfers who get hip, knee, or shoulder replacement surgery to see how and when they return to playing golf. Researchers will track 432 patients for one year after surgery, checking their progress at 6 weeks, 3 months, 6 months, and 12 months. The goal is to bet…

This study is creating a registry to gather information from about 100 patients with undifferentiated connective tissue disease (UCTD), a condition where the immune system attacks the body but doesn't fit a specific diagnosis like lupus. The goal is to track symptoms, lab results…

This study aims to understand how the rheumatoid arthritis drug abatacept (Orencia®) affects the immune system by comparing blood samples from three groups over six months. Researchers will follow 72 people: patients starting abatacept, patients starting a different standard drug…

This study aims to track patients for up to 10 years after they get a new shoulder joint. Researchers want to understand what makes the surgery successful, what problems might occur later, and how it affects patients' daily lives and pain. The study involves collecting informatio…

This study aims to see if thermal camera images can show changes in blood flow and nerve activity after spinal cord stimulation in people with Complex Regional Pain Syndrome (CRPS). Researchers will take pictures of participants' feet before and after the treatment and compare th…

This study is creating a registry to collect health information and optional blood samples from adults with scleroderma. The goal is to better understand this complex disease, its causes, and how it progresses. This knowledge will help researchers develop future treatments for a …