Hospital For Special Surgery, New York

This early-phase trial tests whether adding special cells (E-CEL UVEC) to standard rotator cuff surgery is safe and possible. About 20 adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check for short-term side effects, not…

This study tests whether using a patient's own fat cells (called stromal vascular fraction cells) during rotator cuff surgery can improve healing. About 56 adults aged 45-65 with chronic tears will receive the cells during their operation. The goal is to see if this approach lead…

This study tests whether a drug called abaloparatide can help bones fuse better after spinal fusion surgery. About 96 postmenopausal women and men aged 50+ with low bone mass will receive either the drug or a placebo for 6 months. Researchers will check bone healing, pain, and su…

This study looks at whether surgery to repair a key kneecap ligament (MPFL) works better than non-surgical care for preventing repeat kneecap dislocations in people aged 25 and younger who have dislocated their kneecap once. About 240 participants will be randomly assigned to sur…

This study looks at a new material called Natural Matrix Protein (NMP) used in spinal fusion surgery for people with degenerative lower back problems. About 100 adults who have not gotten better with other treatments will be followed for one year after surgery. The goal is to see…

This study aims to validate a self-report questionnaire that people with Complex Regional Pain Syndrome (CRPS) can fill out at home to measure their symptom severity. Researchers will compare the self-report results with in-person clinical exams to see if the remote tool is accur…

This study aimed to see if telling surgery patients about their high blood pressure would lead to a formal diagnosis of hypertension. Researchers planned to follow up with 108 adults who had elevated blood pressure but no prior diagnosis. However, the study was withdrawn before e…

This study tests whether a very low dose of naltrexone can help ease the severe, chronic pain of Complex Regional Pain Syndrome (CRPS). Forty adults with CRPS will be randomly assigned to receive either the drug or a placebo for six months. The main goal is to see if it's possibl…

This study compares two types of shockwave therapy (radial vs. focused) to see which better reduces morning pain and pain after walking or standing in people with chronic plantar fasciitis. About 114 adults with heel pain lasting over 3 months that hasn't improved with other trea…

This study looks at two ways to numb people for lower back surgery. One group gets standard general anesthesia (fully asleep) plus a nerve block, and the other gets spinal anesthesia (awake but numb from the waist down) plus a nerve block. The goal is to see which approach helps …

This early-stage trial tests whether dalfampridine, a drug used for walking problems in multiple sclerosis, can safely improve walking speed in 35 adults with primary lateral sclerosis or a related upper motor neuron condition. Participants take the drug for 18 weeks and have the…

This study tests a program to help people increase their walking after lumbar spine surgery. Many patients avoid activity due to fear of pain or injury, so the program starts several months after surgery. Researchers will measure changes in weekly walking and pain-related disabil…

This study looks at whether giving the steroid hydrocortisone through a vein can improve how much people can bend and straighten their new knee after total knee replacement surgery. About 132 adults with knee arthritis who are having their first knee replacement will take part. S…

This study follows 3000 people who had hip replacement surgery at Hospital for Special Surgery. Researchers want to learn how patients do over many years, including pain, mobility, and quality of life. Participants simply fill out questionnaires—no extra procedures or treatments …

This study looks back at the medical records of 1000 adults who had foot or ankle surgery at a major orthopedic center. The goal is to understand what causes some patients to stay longer in the recovery room before going home. Researchers will measure how much time and pain medic…

This study follows 3000 people who have had knee replacement surgery at Hospital for Special Surgery. Researchers want to learn how well the new knees work over many years, including pain relief and quality of life. Participants simply fill out questionnaires—no extra procedures …

This study tests whether Intralipid 20%, a fat emulsion, can reverse the numbing effect of local anesthetics like lidocaine and bupivacaine. Eighteen healthy volunteers receive small injections of anesthetic in their thighs, followed by either Intralipid or saline. Researchers me…

This study looks at whether patients and their surgeons have the same expectations for lumbar spine surgery. Researchers will compare survey answers from both groups to see where they agree or disagree. The goal is to improve communication and help patients make more informed dec…