Henry Ford Health System

This early-stage study is testing a new combination treatment for adults with aggressive brain cancer that has come back. After surgery to remove the tumor, doctors inject a specially engineered virus into the brain and give patients oral medications. This is followed by targeted…

This study compares two surgical approaches for prostate cancer. The standard surgery removes the entire prostate but often causes sexual and urinary problems. The newer 'precision' surgery aims to remove most of the prostate while preserving nerves and structures that control th…

This study is testing whether giving the drug azacitidine after a stem cell transplant can help maintain the donor's healthy cells in patients with blood cancers like AML and MDS. The goal is to reduce the risk of the cancer returning by preventing the patient's own cells from ta…

This study is testing whether a medication called tranexamic acid can reduce skin discoloration caused by two conditions: lichen planus pigmentosus and erythema dyschromicum perstans. There are currently no consistently effective treatments for these skin conditions. Researchers …

This early-stage study is testing the safety of a new two-drug combination for people with advanced gastrointestinal cancers (like stomach, colon, or pancreatic cancer) that have continued to grow despite standard treatments. The trial will enroll about 20 patients to find the be…

This study is testing a modified stem cell transplant procedure for adults with blood cancers who do not have a perfectly matched donor. It uses a partially matched (haploidentical) family donor and adds a drug called bortezomib to the standard regimen. The main goal is to see ho…

This study is testing if adding a special patch during shoulder tendon surgery helps the repair heal better and last longer. It will compare surgery with the patch to standard surgery alone. The main goal is to see if the patch leads to a stronger, more intact repair one year aft…

This study is testing whether a smartphone app can help people with alcohol-related liver disease start and stay in treatment programs. The app provides information and helps match patients to treatment options they prefer. Researchers will see if using the app leads more people …

This early-stage study is testing whether adding two pregnancy-related hormones (uhCG/EGF) to a standard drug (cyclophosphamide) can safely prevent graft-versus-host disease (GVHD) after a stem cell transplant from a mismatched donor. The trial will enroll 18 adults with blood ca…

This study aims to prevent heart failure in adults at high risk, primarily due to high blood pressure, in Detroit and Cleveland. It uses mobile health units to reach people in their communities and pairs them with community health workers and pharmacists to improve access to care…

This study tests a new coordinated care program designed to prevent suicide attempts in people recently released from jail. It connects over 5,000 participants to mental health services immediately upon release. Researchers will track if this approach reduces suicide attempts and…

This study aims to see if adding telehealth coaching helps people complete a 6-week digital sleep therapy program for insomnia. Researchers will enroll 600 adults with insomnia and randomly assign them to receive either the standard digital program or the program with extra coach…

This study is testing a new cooling device that fits in the mouth during radiation therapy for throat cancer. The goal is to see if cooling the mouth can help protect a patient's sense of taste, which is often damaged by radiation. Researchers will enroll 15 adults receiving comb…

This study aims to understand how long steroid injections relieve symptoms for people with carpal tunnel syndrome who have mild or normal nerve test results (EMG). Researchers will look back at data from 300 adults who received this standard injection. They will use a standard qu…

This study is testing a mobile app called SHIFT that gives personalized advice to help night shift workers sleep better during the day. Researchers want to see if using the app improves sleep, job satisfaction, and overall health compared to not using it. They're recruiting 300 n…

This study is testing a pain management plan that avoids strong opioids for people recovering from clavicle fracture surgery. It will compare this new plan, which uses a combination of common pain relievers, to the standard opioid-based treatment. The goal is to see if the nonopi…

This study aims to understand how antibiotics given during stem cell transplant affect patients' gut bacteria. Researchers will collect stool samples from 255 transplant patients at different time points to see how their microbiome changes. The goal is to learn if these changes a…

This study tests whether a one-on-one educational session helps Black men with aggressive prostate cancer complete recommended genetic testing. Fifty participants will learn about the benefits and risks of testing from a trained staff member, then decide whether to proceed. The g…

This study aims to develop a better way to measure sleep in people who work overnight shifts. Researchers are testing a new method that uses multiple sensors and machine learning to track sleep more accurately than current standard devices. The study will involve 100 nightshift w…

This study aims to understand why some night shift workers develop sleep problems while others don't. Researchers will test whether a person's tendency to have sleep disrupted by stress (called 'sleep reactivity') is an independent cause of shift work disorder. The study involves…

This study aims to find the best time during a routine pregnancy ultrasound to measure cervical length, which helps predict the risk of early birth. Researchers will compare measurements taken at the beginning versus the end of the ultrasound exam in 550 pregnant participants. Th…

This study aims to create a computer model that can predict how a patient's body temperature changes during a specialized, heated chemotherapy surgery called HIPEC. Researchers will collect detailed temperature and health data from 30 adults undergoing this treatment for abdomina…