George Washington University

This study tests an oral drug called glycerol tributyrate in 24 adults with MELAS or LHON-Plus, two rare diseases that affect how cells produce energy. The goal is to find a safe dose and see if it improves daily activity, walking, and reduces hospital visits. Each participant se…

This study tests whether a 6-month lifestyle program or the drug metformin is better for helping mothers lose weight after having a baby with gestational diabetes. About 60 women who are 3 to 12 months postpartum will track their diet and activity, attend online group sessions, a…

This study tests whether sending text messages can help homeless adults with uncontrolled diabetes better manage their blood sugar and stick to medications. About 100 participants will receive SMS reminders and tips. The goal is to see if this simple, low-cost approach improves h…

This study tests a community program to help youth in Washington, DC imagine and pursue futures without violence. About 1000 young people and their parents will take part. The program offers support and media stories to show appealing, non-violent life paths, aiming to reduce fir…

This study tests a program called HAVEN=CONNECT, designed to prevent suicide and depression in Black youth aged 13-19. The program works with Black churches to train leaders and engage the community. About 240 participants will take part to see if the program reduces depressive s…

This study tests whether taking CoQ10 and glutathione before and after heart surgery can prevent acute kidney injury. About 242 adults having elective bypass surgery will receive either the supplements or a placebo. The goal is to see if this simple approach can protect kidney fu…

This study tests whether community-led programs can reduce intimate partner violence and improve women's economic opportunities in Malawi. About 1,700 women in food-insecure households will take part. The approach combines community mobilization with women's empowerment activitie…

This study tests whether a community program called SASA! Together can reduce intimate partner violence in Malawi. About 4,800 adults aged 18-49 who have been in a romantic relationship will take part. The program works with entire communities to change harmful beliefs and behavi…

This study looks at whether doing everyday tasks with a broken wrist (while in a cast) helps people recover function and feel less pain. About 64 adults with a wrist fracture treated with a cast will be split into two groups: one gets tips on how to safely use their hand, the oth…

This study tests whether a specific nerve block (erector spinae block) can lower pain and the need for painkillers after lung surgery. About 70 adults having lung tumor removal will receive the block or standard care. Researchers will track pain scores and medication use for 24 h…

This study compares two types of nerve blocks (erector spinae vs. intercostal) using a long-lasting anesthetic to control pain after lung surgery. About 120 adults having video-assisted lung procedures will be enrolled. The goal is to see which block provides better pain relief a…

This study tests whether a single injection of long-lasting pain medicine (Exparel) works as well as a continuous drip of pain medicine through small tubes (catheters) for people having surgery after a broken leg, ankle, or thigh bone. About 90 patients will be enrolled, and thei…

This study follows up to 19,000 people with HIV or at high risk for HIV in Washington, DC, to track their health outcomes and quality of care over many years. Researchers will measure how well HIV is controlled (viral suppression) and how quickly preventive services work. The goa…

This study is testing a program to help people in Armenia and Georgia make their homes smoke-free. The goal is to reduce exposure to secondhand smoke, especially for children and non-smokers. About 550 adults who smoke at home or live with a smoker will take part. The program wil…

This study looks at whether community-based mental health services can improve depression, anxiety, and PTSD. About 1,000 adults with mild to moderate psychological distress will receive these services and be tracked over time. The goal is to see if this approach works in real-wo…

This study looks at whether putting a warning label on foods and drinks with non-sugar sweeteners (like diet soda) helps Brazilian parents choose healthier options for their children. About 1,068 parents will pick items like yogurt and cereal bars for their kids, either with no l…

This study aims to see if giving healthy adults a controlled dose of whipworm eggs is safe and can cause a mild infection. Researchers will test different egg doses in 18 volunteers to find the best balance of safety and infection. The goal is to create a reliable model for futur…

This study looks at whether reducing non-nutritive sweeteners (like those in diet sodas) during pregnancy and breastfeeding can lower the risk of infant obesity and improve mom's blood sugar control. Pregnant women who regularly consume these sweeteners will be assigned to either…

This study is watching 3,600 overweight teenagers over time to learn how type 2 diabetes starts. It checks blood sugar, insulin, and other body changes in kids aged 8-15 who are at high risk. The goal is to find early warning signs and better understand the disease, not to test a…

This study is for people with early-stage breast cancer (Stage I-III) who will receive hormone therapy before surgery. Researchers want to see how the cancer responds to this treatment and if they can predict the outcome using blood and tissue samples. Participants will be follow…