One shot vs. tube: which eases broken leg pain better?
NCT ID NCT07221019
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tests whether a single injection of a long-lasting anesthetic (Exparel) can control pain after leg fracture surgery as well as a catheter that delivers pain medicine continuously. About 90 patients with closed leg fractures will receive one of the two methods before surgery. Researchers will measure pain scores and how much opioid painkiller patients need over the next 72 hours.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FRACTURE are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
The George Washington University Hospital
RECRUITINGWashington D.C., District of Columbia, 20037, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine (Exparel) and ropivacaine
What this could lead to
If the single-shot works as well as the catheter, patients could get effective pain relief without needing a catheter tube left in place, simplifying recovery.
What could go wrong
This is a small, early-phase study (90 people) comparing two existing approaches, so it won't prove a major breakthrough. The single-shot may not last as long or control pain as well as the continuous catheter.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.