Genentech, Inc.

This study allowed people with certain cancers (ovarian, basal cell, or colorectal) who had already shown benefit from the drug vismodegib in earlier trials to keep receiving it. The main goal was to track safety and side effects over time. Only 19 patients took part, all of whom…

This study tested an experimental drug called astegolimab in over 1,300 people with chronic obstructive pulmonary disease (COPD) who had frequent flare-ups. Participants received either the drug or a placebo alongside their usual COPD treatments. The main goal was to see if asteg…

This study tested an experimental drug called mosunetuzumab, given alone or with another drug (atezolizumab), in 713 people with B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia that had come back or stopped responding to prior treatments. The goal was to find the safe…

This study tested a drug called vismodegib in 104 people with advanced basal cell carcinoma, a type of skin cancer that had spread or could not be surgically removed. All participants took the drug daily until their cancer worsened, side effects became too severe, or they chose t…

This study looked at how well the drug ocrelizumab controls relapsing multiple sclerosis in Black and Hispanic patients. About 179 participants received the treatment and were monitored for relapses, disability progression, and brain lesions over 48 weeks. The goal was to underst…

This early-phase study tested the safety of a new drug called GDC-1971 when given with either osimertinib (for lung cancer) or cetuximab (for colorectal cancer). It involved 10 adults with advanced cancer that had spread or couldn't be removed. The main goal was to check for side…

This study tested whether adding tiragolumab to atezolizumab works better than atezolizumab alone for people with advanced non-small cell lung cancer who had not received prior treatment. 135 participants were randomly assigned to receive either the combination or a placebo plus …

This study tested an experimental drug called KPL-716 in 240 adults with prurigo nodularis, a skin condition that causes hard, itchy bumps. The goal was to see if the drug could safely reduce itching better than a placebo. Participants received either the drug or a placebo, and t…

This study tested an experimental drug called GDC-6599 in 49 adults with long-term cough that doesn't go away with standard treatments. The goal was to see if the drug could reduce how often people coughed and how bad the cough felt. Participants took the drug or a placebo for a …

This study looked at how the drug divarasib is processed in people with different levels of liver function. 31 healthy volunteers and people with mild to severe liver problems received a single dose. The goal was to measure drug levels in the blood and check for side effects, not…

This study looked at how taking ZN-A-1041 tablets with food or a stomach-acid drug (rabeprazole) changes the amount of medicine in the blood. Twenty-four healthy adults took the drug under different conditions to measure absorption. The goal was to gather information for future d…