Fudan University

Researchers are testing whether adding brain radiotherapy to PD-1/PD-L1 inhibitors and chemotherapy helps people with untreated stage IV non-small cell lung cancer that has spread to the brain. The trial enrolls about 40 adults whose tumors lack common driver mutations and whose …

This trial tests whether removing lung nodules with non-intubated video-assisted thoracic surgery, which avoids a breathing tube and ventilator, helps patients recover faster and feel better than traditional intubated surgery. Researchers will compare symptom burden, quality of l…

This study tested whether adding a Chinese herbal formula (QingyiHuaji) to standard chemotherapy helps people with stage IV pancreatic cancer live longer. About 305 adults with advanced pancreatic cancer were randomly assigned to receive either the herbal formula plus chemo or a …

This study looks at how well different immunochemotherapy combinations, such as RCHOP, BR, and RCVP, work for people with small B-cell non-Hodgkin lymphoma. Researchers will track 206 adults with this type of lymphoma to see how many respond to treatment and how long they stay fr…

This phase III trial compares two radiation schedules for women with high-risk breast cancer who have had a mastectomy. One group receives hypofractionated radiation, which uses fewer but larger daily doses over a shorter period. The other receives conventional radiation, with sm…

This study compares 4 months versus 6 months of chemotherapy (capecitabine and oxaliplatin) in 1024 stomach cancer patients who had surgery. The goal is to see if the shorter treatment works just as well to prevent cancer from coming back, while causing fewer side effects. Partic…

This study looked at whether tiny plastic particles (microplastics) we encounter daily might contribute to obesity and gut problems. Researchers gave 96 overweight or obese adults either a probiotic supplement or a placebo to see if the probiotic could reduce the harmful effects …

This phase 2 trial is testing whether a combination of two chemotherapy drugs (nab-paclitaxel and cisplatin) plus an immunotherapy drug (camrelizumab) can help people with metastatic triple-negative breast cancer live longer without their disease getting worse. The study enrolls …

This pilot study tests whether adding a special heat therapy (multimodal thermal therapy) to standard chemotherapy and immunotherapy can help the immune system better recognize and attack HER2-negative breast cancer. The study enrolls women aged 18–70 with certain subtypes of bre…

This study tested whether taking oral chemotherapy pills (vinorelbine or capecitabine) along with the targeted drug trastuzumab can help prevent breast cancer from coming back in women with small, HER2-positive tumors that have not spread to lymph nodes. The 182 participants took…

This study looked at whether using epidural anesthesia (a numbing shot in the back) during pancreatic cancer surgery helps people live longer and stay cancer-free longer. About 540 adults having surgery for pancreatic cancer took part. The goal was to see if this type of pain con…

This study looked at 708 patients with a rare, low-grade pancreatic tumor called solid pseudopapillary neoplasm. Researchers compared a less invasive surgery that saves healthy pancreas tissue to a more extensive surgery that removes more of the organ. They also examined whether …

This study tested a combination of two drugs—interferon-gamma monoclonal antibody and dexamethasone—in 22 adults with a severe immune condition called refractory secondary HLH. The goal was to see if the treatment helps patients recover and how safe it is. Participants received t…

This completed trial tested whether a mix of 43 plant polyphenols can counteract health damage from environmental pollutants. 98 adults took either the polyphenol supplement or a placebo for a period. Researchers measured changes in gut health, inflammation, and blood markers to …

This phase 2 trial tested a combination of three drugs—camrelizumab (an immunotherapy), cetuximab (a targeted therapy), and chemotherapy—as a first treatment for people with head and neck cancer that has come back or spread. The study enrolled 41 participants and measured how man…

This study tested whether adding a diabetes drug (polyethylene glycol loxenatide) to a hormone-releasing IUD (LNG-IUS) helps women with a precancerous uterine condition called endometrial atypical hyperplasia. The 30 participants were all obese and wanted to preserve their fertil…

This early-stage trial tested the safety and tolerability of a chemotherapy drug called raltitrexed when given as a heated solution directly into the abdomen (HIPEC) in 30 patients with colorectal cancer. The goal was to find the highest safe dose and understand how the drug beha…

This study tested a combination of three drugs (capecitabine, lenvatinib, and tislelizumab) given after surgery to 65 adults with biliary tract cancer. The goal was to see if this treatment could help keep the cancer from coming back. The results focus on how long patients lived …

This phase 2 trial tested the drug serplulimab (an immunotherapy) combined with standard chemotherapy in 30 people with stage II-IIIA non-small cell lung cancer that could be surgically removed. The treatment was given before and after surgery to see if it could shrink tumors and…

This trial tests whether a special CT scan, called CT perfusion, can measure blood flow in the feet of people with critical limb ischemia, a severe blockage of leg arteries. Researchers will scan 80 patients before and three days after they undergo surgery to restore blood flow. …

This study tests whether limiting eating to a 10-hour window each day can lower the chance of developing gestational diabetes in pregnant women at high risk. Researchers will compare this approach to usual eating habits over 3 months in 240 women. The goal is to see if this simpl…

This trial compares two minimally invasive surgical techniques for removing the lower part of the stomach in people with gastric cancer: laparoscopy-assisted distal gastrectomy (LADG) and totally laparoscopic distal gastrectomy (TLDG). The goal is to see which approach leads to b…

This study looked at whether it's safe to stop changing wound dressings after gastrointestinal cancer surgery. Over 1,100 adults were randomly assigned to either have their wound dressing removed after 48 hours and left uncovered, or to receive routine dressing changes every two …

This study tested whether using less dexamethasone (a steroid) along with two other anti-nausea drugs (NEPA and olanzapine) works as well as the standard full-dose steroid approach. 644 adults receiving strong chemotherapy were enrolled. The goal was to see if the reduced-steroid…

This study looked at whether Huaier Granule, a traditional Chinese medicine, can reduce protein in the urine—a sign of kidney damage—caused by anti-angiogenesis targeted therapy in 76 adults with advanced liver or bile duct cancer. Participants took the granule for 8 weeks, and r…

This study tested whether a nerve block called erector spinae plane block can reduce pain after breast cancer surgery with implant reconstruction. 100 patients were randomly assigned to receive the block or not. The main goal was to measure pain scores 6 hours after surgery. The …

Researchers at Fudan University are studying how three strengths of the local anesthetic ropivacaine affect lung ventilation when used for intercostal nerve blocks during breast quadrantectomy. The trial enrolls 67 adults scheduled for this surgery and randomly assigns them to re…

This study looks at whether metformin, a common diabetes drug, is linked to muscle strength, muscle mass, and physical function in people aged 60 and older with type 2 diabetes. Researchers will compare older adults who have taken metformin for at least three months to those on o…

This study aims to create a simple risk score to identify patients with pancreatic neuroendocrine tumors (PanNETs) who are at high risk of their cancer returning after surgery. Current methods are not very good at predicting individual risk. Researchers will analyze data from ove…

This study follows 600 Chinese women with early-stage HER2-positive breast cancer to see how anti-HER2 treatment affects their quality of life over a year. Participants fill out questionnaires about physical, emotional, and social well-being. The goal is to understand real-world …

This study looked at 4000 people with advanced lung cancer who had a specific gene mutation (EGFR) and were taking a targeted pill. The goal was to find the best time to add focused radiation to shrink any remaining tumors. Researchers tracked when tumors shrank the most and wher…

This study looked at whether giving 7-11-year-old children in Shanghai a daily breakfast with fruits and vegetables could improve their thinking, mood, and attention. Over 250 kids took part, receiving a balanced breakfast every day for 12 weeks. Researchers measured changes in c…

This study looked at how ozone, a common air pollutant, affects the skin of healthy young adults. Forty participants had their forearms exposed to either ozone or clean air for two hours. Researchers measured changes in skin chemicals, hydration, moisture loss, and pH to understa…

This study analyzed medical records from 1197 patients in China with advanced esophageal cancer who received immunotherapy (anti-PD-1) plus chemotherapy as their first treatment. The goal was to see how long patients lived and how long the cancer stayed under control in everyday …

This completed study from Fudan University looked at 200 older adults with COPD who also have sarcopenic obesity — a condition where muscle loss and excess fat occur together. Researchers used a device called InBody S10 to measure body composition and phase angles, aiming to buil…

This study involved 562 premenopausal women in China with hormone receptor-positive breast cancer who received a GnRHa injection to suppress ovarian function after surgery. Researchers measured their quality of life and how well they followed the treatment plan using questionnair…

This study looked at nearly 3,000 people who had non-advanced colon polyps (small, low-risk growths) found during their first screening colonoscopy. Researchers wanted to see if having more of these polyps increased the chance of developing advanced growths or cancer later. The g…

This completed study from Fudan University used a deep learning model to predict whether stomach cancer will come back after surgery. Researchers analyzed data from 5,000 patients across multiple hospitals in Eastern Asia. The model showed strong ability to identify early recurre…