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Ozone's hidden impact on skin revealed in new study

NCT ID NCT06932419

Knowledge-focused Sponsor: Fudan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how ozone, a common air pollutant, affects the skin of healthy young adults. Forty participants had their forearms exposed to either ozone or clean air for two hours. Researchers measured changes in skin chemicals, hydration, moisture loss, and pH to understand the immediate effects of ozone on skin health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ozone exposure
What this could lead to
If successful, this could help us understand how air pollution affects skin, potentially guiding future skincare or public health advice.
What could go wrong
This is a small, early-stage study with only 40 healthy young adults, so results may not apply to everyone. It measures short-term effects, not long-term health impacts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Apr 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Living in Shanghai during the study period; * Having healthy skin conditions on both forearms. Exclusion Criteria: * Subjects with a history of smoking and alcohol abuse; * Subjects with a regular use of medication and dietary supplements within 2 months prior to enrollment; * Subjects with severe skin diseases, such as atopic dermatitis, eczema, or severe acne; * Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, or atopy, or history of allergic reactions within 2 months prior to enrollment; * Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, or hypertension; * Subjects with respiratory diseases, such as asthma, acute or chronic bronchitis, or pneumonia; * Subjects with chronic diseases, such as diabetes, chronic hepatitis, or kidney disease; * Subjects with cutaneous abnormalities on forearm, such as severe pigmentation, multiple nevus, or tattooing; * Subjects who underwent cosmetic intervention on forearms within 2 months prior to enrollment, such as whitening treatments, UV exposure therapies, depigmentation procedures, or tanning; * Females in pregnancy or lactation status.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Skin health

Contacts and locations

Locations

  • Department of Environmental Health, School of Public Health, Fudan University

    Shanghai, Shanghai Municipality, 200032, China

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