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New combo reduces steroid use in chemo side effect prevention

NCT ID NCT06331520

First seen Apr 23, 2026 · Last updated Jun 18, 2026 · Updated 8 times

Summary

This study tested whether using less dexamethasone (a steroid) along with two other anti-nausea drugs (NEPA and olanzapine) works as well as the standard full-dose steroid approach. 644 adults receiving strong chemotherapy were enrolled. The goal was to see if the reduced-steroid combo could still prevent vomiting and the need for rescue medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Cancer

    Shanghai, Shanghai Municipality, 200043, China

Conditions

The condition(s) this trial relates to.

chemotherapy-induced toxicity Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.