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Colon polyp count linked to future cancer risk, study finds

NCT ID NCT07302139

Knowledge-focused Sponsor: Fudan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at nearly 3,000 people who had non-advanced colon polyps (small, low-risk growths) found during their first screening colonoscopy. Researchers wanted to see if having more of these polyps increased the chance of developing advanced growths or cancer later. The goal is to help doctors decide how often patients need follow-up colonoscopies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,955 people

The number who actually took part.

Started

Sep 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individuals who underwent their first-time screening colonoscopy between 2012 and 2023 at the endoscopy centers of Huadong Hospital and Shanghai Tongji Hospital, and who completed at least one surveillance colonoscopy.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * First-time screening colonoscopy * Only non-advanced adenomas (no villous features, no high-grade dysplasia, and diameter \<10 mm) were detected during first-time screening colonoscopy * Individuals with at least one surveillance colonoscopy * Complete electronic medical record and pathology information Exclusion Criteria: * Inadequate bowel preparation (BBPS \< 6) * Emergency colonoscopy * History of colorectal cancer * Incomplete pathology information or incompletely resected polyps * Screening colonoscopies performed by endoscopists with a low dynamic adenoma detection rate (ADR \< 15%) * Follow-up duration \< 6 months

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Conditions

The condition(s) this trial relates to.

colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenoma

Contacts and locations

Locations

  • Huadong hospital, Fudan university

    Shanghai, Shanghai Municipality, 200040, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.