Fondazione Irccs Policlinico San Matteo Di Pavia

This study tested a new inhaled treatment for bronchiolitis obliterans syndrome (BOS), a form of chronic rejection that often occurs after a lung transplant. The treatment uses tiny particles called liposomes to deliver the drug everolimus directly to the lungs, aiming to reduce …

This study tested new software on ultrasound machines to measure liver fat in people with non-alcoholic fatty liver disease (NAFLD). The goal was to see if these ultrasound results matched the standard Fibroscan test. 25 adults took part. The approach is non-invasive and could ma…

This study looked at whether a medicine called Evusheld could help prevent COVID-19 in people with weakened immune systems who did not get protection from vaccines. 88 adults who had not made antibodies after vaccination took part. The goal was to see how many got sick with COVID…

This small study looked at whether citicoline, a supplement that supports nerve health, could improve vision in people with glaucoma after they had surgery to lower eye pressure. Six adults with open-angle glaucoma who needed surgery were given either citicoline or a placebo. The…

This study looked at whether a specific cell count in the blood can predict acute graft-versus-host disease (GVHD) in adults receiving a stem cell transplant for blood cancer. Researchers measured endothelial cells in blood samples from 50 patients before transplant. The goal was…

This study looked at compassion fatigue, burnout, and stress in 159 healthcare workers (doctors, nurses, and assistants) in the Emergency Room and Intensive Care Unit. Researchers measured their well-being before and after they took part in group discussions designed to find ways…

This study looked at 70 adults with acute myeloid leukemia (AML) to understand why more than half of patients with favorable-risk genetics still relapse. Researchers focused on the bone marrow's support cells (mesenchymal stem cells) and how they might help leukemia stem cells su…

This study looked at 15 older adults with acute myeloid leukemia (AML) who were getting a standard drug combo (azacitidine or decitabine plus venetoclax). Because these drugs can lower infection-fighting white blood cells, patients often take an antifungal called posaconazole. Th…

This study looked at 30 people newly diagnosed with cardiac AL amyloidosis, a rare disease where abnormal proteins damage the heart. Researchers used advanced MRI, echocardiogram, and PET scans to see if these imaging tools could predict survival and measure how well chemotherapy…

This study looked at 581 children aged 1 to 16 in the hospital to see how often they picked up MRSA bacteria in their nose. Researchers wanted to know if getting antibiotics during the hospital stay made it more likely to get MRSA. The goal is to help doctors use antibiotics more…

This study looked at 70 people—some with primary myelofibrosis (a rare bone marrow disorder) and some healthy—to understand how certain immune cells called MDSCs fuel inflammation and blood vessel growth in the disease. Researchers measured these cells in blood and spleen samples…

This study aims to identify biological markers that can predict how well patients with AL amyloidosis will respond to first-line therapies. Researchers will analyze data and leftover samples from 250 participants to understand drug resistance and improve treatment personalization…

This study looked at how well early COVID-19 antiviral treatments work in cancer patients who are on active cancer therapy. Researchers tracked 112 patients to see if these treatments reduced hospitalizations and deaths. The goal is to fill knowledge gaps and improve care for thi…

This study looked at whether a regional guideline for spotting and treating sepsis early helped pregnant or postpartum women in Italy. Researchers compared hospital stays, deaths, and complications in 52 women before and after the guideline was put in place. The goal was to see i…

This study used computer simulations to compare three types of radiation (photons, protons, and carbon ions) for treating a dangerous heart rhythm called ventricular tachycardia. Researchers created treatment plans based on real heart scans from 23 patients who were scheduled for…

This study looked at 445 people with mild pancreatitis caused by gallstones. Researchers compared those who had their gallbladder removed during the same hospital stay versus those who had surgery weeks later. The goal was to see if earlier surgery lowers the chance of gallstone …

This study created a database of 60 heart transplant patients to track their health over time. The goal was to learn about the main causes of death, illness, and hospital visits after a heart transplant. No new treatments or medications were tested—the focus was purely on gatheri…

This study tested different ultrasound-based techniques to measure liver stiffness in 72 adults with chronic liver disease. The goal was to see how well these newer methods compare to an established one, all without needing a needle biopsy. The results help doctors choose the bes…

This study looked at 80 teenagers aged 14 to 17 who were experiencing emotional distress. Researchers measured their anxiety levels using a questionnaire and offered a 10-session counseling program to those who needed it. The goal was to better understand teen mental health and s…