Fondazione Irccs Policlinico San Matteo Di Pavia
Clinical trials sponsored by Fondazione Irccs Policlinico San Matteo Di Pavia, explained in plain language.
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Inhaled Nano-Treatment targets lung scarring in new study
Disease control OngoingThis study is testing a new inhaled treatment for pulmonary fibrosis, a condition where the lungs become scarred and stiff. The treatment uses tiny fat bubbles (liposomes) coated with a substance that helps them target the cells causing inflammation and scarring. The goal is to s…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New DNA test could diagnose lung infections in hours, not days
Diagnosis OngoingThis study tests a new method that uses real-time DNA sequencing to quickly identify bacterial infections in the lungs. Researchers will compare how fast and accurately this new approach works compared to standard lab cultures. The study involves 100 adults with suspected lower r…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated May 19, 2026 11:59 UTC
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Hidden hepatitis b risk in cancer immunotherapy under scrutiny
Knowledge-focused OngoingThis study watches 60 cancer patients who have a hidden form of hepatitis B (occult infection) to see if immunotherapy treatments cause the virus to become active again. Researchers will use new blood tests to detect early signs of reactivation. The goal is to better understand a…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 26, 2026 02:27 UTC
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Blood clot clues may predict pain treatment success
Knowledge-focused ENROLLING_BY_INVITATIONThis study is for adults with Complex Regional Pain Syndrome (CRPS), a condition that causes long-term pain. Researchers want to see if certain blood clotting factors are linked to how well patients respond to a treatment called neridronic acid. The goal is to better understand t…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 26, 2026 02:23 UTC
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Gene clues could improve treatment for organ rejection
Knowledge-focused OngoingThis study looks at gene activity in blood cells from 30 kidney or lung transplant patients who have chronic rejection. Researchers want to find out why some patients respond well to a treatment called extracorporeal photoapheresis (ECP) while others do not. By comparing gene pro…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 26, 2026 02:20 UTC
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New study seeks to predict surgical risks in throat cancer patients
Knowledge-focused OngoingThis study looks at 400 people who had surgery for throat cancer to find out why some develop a leak called a fistula after the operation. Researchers want to see if using a tissue flap during surgery or having low muscle mass (sarcopenia) affects the risk. The goal is to better …
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 26, 2026 02:18 UTC
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Gut check: could your microbiome make immunotherapy work better?
Knowledge-focused OngoingThis study looks at how the bacteria in your gut might influence how well immunotherapy works for solid tumors. Researchers will collect stool and blood samples from 70 cancer patients starting immunotherapy to track changes in gut bacteria and immune markers. The goal is to unde…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 26, 2026 02:16 UTC
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Fungal resistance study pulled before it began
Knowledge-focused TerminatedThis study aimed to understand which types of Candida fungus cause bloodstream infections and how drug resistance changed during the COVID pandemic. It planned to enroll adults over 18, but was withdrawn before any participants joined. No results were collected.
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Blood cancer Patients' immune system under microscope for COVID-19 clues
Knowledge-focused OngoingThis study examines whether people with certain blood cancers (myeloproliferative neoplasms) have autoantibodies that block a key immune protein, type I interferon. Researchers want to see how common these autoantibodies are and if they relate to worse COVID-19 outcomes. About 21…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Researchers compare flap types in repeat throat cancer operations
Knowledge-focused OngoingThis study looks at 100 people with recurrent hypopharyngeal cancer who need a second surgery (salvage surgery) with a flap to rebuild the area. The goal is to see if the type of flap used (free or pedicled) is linked to different complication rates. The study only observes past …
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC
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Dialysis filter showdown: which one protects your immune cells best?
Knowledge-focused OngoingThis study looks at how different dialysis filters impact immune cell damage in people on hemodialysis. About 30 patients will try two types of filters to see which one better reduces harmful substances in the blood and protects white blood cells. The goal is to understand how di…
Phase: NA • Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC