Cmc Ambroise Paré
Clinical trials sponsored by Cmc Ambroise Paré, explained in plain language.
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Could cheap steroids be a lifesaver for shock patients?
Disease control CompletedThis study tested whether giving low doses of two steroids (hydrocortisone and fludrocortisone) helps adults with cardiogenic shock, a life-threatening condition where the heart can't pump enough blood. Researchers measured how many days patients were alive and off strong heart-s…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 26, 2026 05:14 UTC
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Heart surgery breathing study aims to cut lung failure risk
Disease control CompletedThis study tested two ways of using a breathing machine during heart surgery that requires a heart-lung machine. One group received no breaths during that time, while the other received small, gentle breaths. The goal was to see which approach better prevents serious lung complic…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 26, 2026 04:35 UTC
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Back surgery combo shows promise for spine slip
Disease control CompletedThis study looked at 87 adults with a spine condition called isthmic spondylolisthesis, where one vertebra slips forward. They all had a two-part surgery to fuse the bones together. The results showed the surgery is safe and helps restore normal spine shape and nerve space.
Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New drug may stop common heart rhythm problem after surgery
Prevention CompletedThis study tested a low-dose drug called landiolol to prevent atrial fibrillation (a type of irregular heartbeat) after heart surgery. About 400 non-Asian adults who had heart surgery took part. The goal was to see if landiolol could lower the chance of developing this complicati…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Prevention
Last updated May 26, 2026 05:06 UTC
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Nerve block may cut anesthetic use during heart surgery
Symptom relief CompletedThis study tested whether a nerve block given before open-heart surgery (coronary artery bypass) could reduce the amount of strong anesthetics needed to keep heart rate and blood pressure stable during the procedure. 35 adults participated. The approach aims to improve safety and…
Phase: PHASE4 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 05:14 UTC
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Virtual reality vs. gas: a new way to ease pain after heart surgery?
Symptom relief CompletedThis study looked at whether using virtual reality (VR) can help reduce pain and anxiety when chest tubes are removed after heart surgery. It involved 200 adults who had recently had heart surgery. The researchers compared VR to a standard gas treatment (nitrous oxide) to see whi…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 05:11 UTC
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New numbing technique could make hand surgery simpler and safer
Symptom relief CompletedThis study tested whether a newer numbing method called WALANT (injecting numbing medicine directly into the wrist) works as well as the standard axillary block (numbing the whole arm) for carpal tunnel release surgery. 130 adults having endoscopic carpal tunnel release took part…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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Heart surgery patients may get relief from Post-Op constipation with naloxegol
Symptom relief CompletedThis study tested whether naloxegol, a drug used for opioid-induced constipation, can shorten the time it takes for bowel function to return after heart surgery. 305 adults undergoing cardiac surgery with a heart-lung machine were randomly assigned to receive naloxegol or a place…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 05:04 UTC
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No opioids needed? new anesthesia method aims for better hip surgery recovery
Symptom relief CompletedThis study tested whether using a drug called dexmedetomidine instead of opioids during hip replacement surgery could reduce pain and the need for strong painkillers afterward. 80 adults having hip replacement took part. The goal was to see if this opioid-free approach leads to l…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 05:03 UTC
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No tourniquet, less pain: new numbing combo tested for hand surgery
Symptom relief CompletedThis study tested whether a numbing method called WALANT (which uses only local anesthetic and no tourniquet) could make carpal tunnel release surgery more comfortable. Sixty adults having endoscopic carpal tunnel release were randomly assigned to receive either the standard nerv…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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Video glasses may reduce sedation during IVF egg retrieval
Symptom relief CompletedThis study tested whether using HappyMed Video Glasses to watch movies during egg retrieval for IVF could reduce the amount of sedative medication needed. 36 women participated, with some using the glasses and others receiving standard care. The goal was to see if distraction cou…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 18, 2026 12:13 UTC
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Knee surgery pain relief gets a boost from sedative drug
Symptom relief CompletedThis study tested whether giving a drug called dexmedetomidine before knee replacement surgery could make pain relief from nerve blocks last longer. 94 adults having planned knee replacement took part. The goal was to see if the drug could delay the need for strong painkillers af…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Breathing easy: No-Mask anesthesia induction tested
Knowledge-focused CompletedThis study tested a new way to give anesthesia without using a face mask. Normally, patients breathe pure oxygen through a tight-fitting mask before and during the start of anesthesia. The researchers wanted to see if a device that delivers warm, moist oxygen through the nose (Op…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 05:10 UTC
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AI could make heart monitoring easier for breast cancer patients
Knowledge-focused CompletedThis study tested an artificial intelligence (AI) model to measure heart rhythm changes (QTc interval) in 70 women with breast cancer starting the drug ribociclib. The goal was to see if the AI could match the accuracy of standard ECG monitoring, potentially allowing simpler devi…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 05:07 UTC
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Thymus gland may hold key to COVID-19 severity
Knowledge-focused CompletedThis study looked at how the thymus gland, which produces immune cells called T cells, affects COVID-19 severity. Researchers examined 85 hospitalized patients to see if genetic differences in thymus function are linked to worse lung damage. The goal was to better understand why …
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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Routine shock test during ICD swap: helpful or just extra risk?
Knowledge-focused CompletedThis study followed 143 people who needed a new implantable cardioverter-defibrillator (ICD) to see if routine defibrillator testing during the replacement procedure is safe and useful. Researchers checked for device or lead problems by measuring abnormal shock impedance values. …
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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Heart surgery patients wear wristbands to measure recovery
Knowledge-focused CompletedThis study tested whether a simple electronic wristband could help doctors understand how well patients recover after heart surgery. 137 adults wore the wristband for two months after leaving the hospital, and it counted their daily steps. The goal was to see if step counts could…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Scientists map hidden shoulder tendon that may explain mysterious injuries
Knowledge-focused CompletedThis study looked at a recently discovered tendon in the shoulder called the delto-pectoral tendon (DPT). Researchers used ultrasound to see and measure this tendon in 46 adults with upper limb problems. The goal was to understand its role in the shoulder's structure and how it m…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 26, 2026 04:34 UTC
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Heart surgery leaves one in six with lingering diaphragm trouble
Knowledge-focused CompletedThis study looked at how often the diaphragm (the main breathing muscle) remains weak after heart surgery. Researchers followed 157 adults who had open-heart surgery and used ultrasound to check diaphragm movement. The goal was to find out how common persistent diaphragm problems…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Liver ultrasound may predict heart failure after surgery
Knowledge-focused CompletedThis study looked at 32 adults who had heart surgery to see if a liver ultrasound could help find right-sided heart problems. Right heart issues are common after surgery and can lead to kidney or liver failure. The researchers measured blood flow in the liver and compared it to s…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Can a stiff limb deepen your hypnosis? new study investigates
Knowledge-focused CompletedThis study looked at whether making a person's arm or leg stiff (catalepsy) helps them go into a deeper hypnotic trance. Researchers measured changes in the body's 'rest and digest' nervous system using a special monitor. 90 healthy volunteers took part to see if this common hypn…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC
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Can a simple ultrasound predict bladder leak severity?
Knowledge-focused CompletedThis study looked at whether ultrasound measurements of the urethra can help predict how severe urinary incontinence is in women. Researchers measured the length and angle of the urethra in 50 adult women. The goal was to see if these measurements could be used to forecast incont…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC