Central Hospital, Nancy, France

This study compares a low dose (0.5 mg) of epinephrine to the standard dose (1 mg) given during emergency treatment for out-of-hospital cardiac arrest. The goal is to see if the lower dose helps more people survive with good brain function. About 4,336 adults will take part, and …

This study tests whether a deep-learning computer tool can improve the quality of brain scans for Alzheimer's disease when using lower radiation doses. Researchers will compare standard scans to those processed by the algorithm in 40 patients with memory problems. If successful, …

This study looks at whether a single dose of the antibiotic ceftriaxone can prevent early pneumonia in patients with serious brain injuries who need a breathing machine. Researchers will check if the drug reaches high enough levels in the blood to kill bacteria, especially in pat…

This study explores whether a hypnosis session can help intensive care unit (ICU) patients successfully come off a breathing machine (mechanical ventilator). The goal is to see if hypnosis is feasible and if it can reduce pain and anxiety during the weaning process. Thirty adult …

This study looks at 400 adults with primary hyperparathyroidism (a calcium disorder) who are scheduled for parathyroid surgery. Researchers will measure a hormone called aldosterone, which helps control blood pressure, before surgery and at 3, 6, and 12 months after. The goal is …

This study looks back at medical records of about 60 people with primary immune deficiencies who also have lymphoproliferation (swollen lymph nodes or organs). The goal is to see what serious health events happen over time, such as death, cancer, or organ damage. Researchers hope…

This study looks back at the egg donation process at Nancy University Hospital after France updated its bioethics laws in 2021. Researchers will review the records of about 60 women who started the donation process to see how many actually donated eggs and how long it took. The g…

This study tests whether a new collimator (a part that filters gamma rays) can improve whole-body scans in a special camera used for cancer imaging. 18 adults with multiple cancer spots will get an extra scan to see if the new part makes pictures sharper and more useful. The goal…

This study looks at how blood phenylalanine (Phe) levels impact the thinking, emotions, and daily functioning of 30 adults with PKU. Researchers want to understand why some patients with high Phe levels have no major brain problems. No treatment is given—only questionnaires and o…

This study looks at how often people with drug-resistant focal epilepsy experience mild psychotic symptoms after a seizure, especially during a hospital stay for brain monitoring. Researchers will follow 110 patients for two months after discharge, using interviews and questionna…

This study looks at a protein called TREM-1 in liver cells to see if it can help doctors tell how severe a patient's alcoholic hepatitis is and predict who will respond to treatment. Researchers will compare TREM-1 levels in 300 people with severe alcoholic hepatitis or other liv…

This study looks at whether the usual dose of an antibiotic (piperacillin/tazobactam) is enough to prevent infections during major liver or pancreas surgery. About 60 adults having these surgeries will have their antibiotic levels measured. The goal is to see if current dosing wo…

This study will use MRI scans to measure the electrical properties of the head, neck, and torso in 120 healthy volunteers across three age groups: children (6-12), adults (20-40), and seniors (70+). The goal is to create a detailed database of how these properties change with age…

This study will follow 522 adults across Europe who are having surgery to remove an adrenal gland tumor. The goal is to see how often serious heart problems happen in the 30 days after surgery, and to find out what factors might increase that risk. By collecting this information,…

This study looks at whether measuring a specific antibody (anti-Ro52) in the blood can help predict serious complications in people with Sjögren's syndrome. Researchers will follow 150 adults with Sjögren's to see if higher antibody levels are linked to severe events like organ d…

This study looks at why finger-stick blood tests (capillary) sometimes give different results than standard arm blood draws (venous) for people with antiphospholipid syndrome who take blood thinners. Researchers will compare two finger-stick devices to the usual lab test in 150 a…

This study looks at intestine tissue removed during surgery from 60 adults with Crohn's disease. Researchers will use special MRI scans and lab tests on the tissue to better understand the difference between active inflammation and permanent scarring. The goal is to improve futur…

This study looks at older adults (70+) admitted to the ICU with a brain bleed from a burst aneurysm. Researchers will review medical records to find factors that predict whether a patient will recover or have a poor outcome at 6 months and 1 year. The goal is to help doctors make…