Beijing Friendship Hospital

This study tests a new combination of drugs (iparomlimab and tuvonralimab, called QL1706) plus chemotherapy for people with advanced stomach or gastroesophageal junction cancer that hasn't been treated yet. The goal is to see if the combo can shrink tumors and control the disease…

This study tests a new surgery approach for early gastric cancer that uses a fluorescent dye to find the first lymph nodes where cancer might spread. By removing only those nodes instead of many, doctors hope to preserve more stomach function and improve quality of life. The tria…

This study tests whether adding the immunotherapy drug tislelizumab to standard chemoradiation helps more people with locally advanced rectal cancer achieve a complete response. About 375 adults will receive either chemoradiation alone or combined with tislelizumab, followed by c…

This study tests whether a combination of four drugs (adebrelimab, apatinib, oxaliplatin, and tigio) can shrink advanced stomach or gastroesophageal junction cancer enough to allow surgical removal. About 49 adults with unresectable stage III or IV cancer will receive 2 to 8 cycl…

This study tests a drug called golidocitinib for people with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system attacks the body. About 28 adults aged 14 to 70 with new or returning HLH will take the drug alone. The goal is to see if it can improve…

This study tests a new bioartificial liver device (CiPS-BAL) in 12 people with liver failure or small-for-size syndrome. The main goal is to see if the device is safe and tolerable. Researchers will also check how it affects liver function and other health measures. The device us…

This study tests if giving terlipressin during kidney transplant surgery helps maintain blood pressure better than standard drugs. About 150 adults with kidney failure will be randomly assigned to receive either terlipressin plus dobutamine or dobutamine alone. The goal is to see…

This study compares a new nerve-sparing surgery (TLSA) to the standard surgery (TBSA) for people with a hiatal hernia and acid reflux that doesn't improve with medication. The goal is to see if TLSA leads to better quality of life by avoiding damage to a nerve that controls stoma…

This study tests whether combining two drugs, golidocitinib and selinexor, can control chronic active Epstein-Barr virus disease (CAEBVD). About 28 adults with active symptoms will receive the treatment. The goal is to reduce virus levels and improve disease activity.

This study compares two blood thinners—rivaroxaban and warfarin—in people with a kidney condition called idiopathic membranous nephropathy who are at high risk for dangerous blood clots. About 134 participants will take one of the medications for 6 months to see which better prev…

This study tests whether a smartphone-based rehab program can reduce complications and improve recovery in people with stomach cancer who receive chemotherapy before surgery. About 186 participants will follow the program from before surgery until four weeks after leaving the hos…

This early-stage study is testing a new medication for Restless Legs Syndrome (RLS), a condition that causes uncomfortable urges to move the legs. About 20 adults with moderate to severe RLS will take the drug twice daily for 12 weeks. Researchers will measure changes in symptom …

This study aims to better understand primary biliary cholangitis (PBC), a chronic liver disease, in Chinese patients. Researchers will track 4,000 participants over time to see how symptoms like fatigue and itching affect their lives and how well treatments work. The goal is to i…

This study looks at how the eyes, brain, and kidneys interact in adults with chronic kidney disease (CKD). Researchers will use non-invasive MRI scans and eye imaging to see if changes in the brain and retina are linked to thinking problems and kidney function. About 1,500 partic…

This study looks at two types of anesthesia—conscious sedation and general anesthesia—used during painless stomach exams (gastroscopy) in frail patients aged 65 and older. The goal is to see which method leads to fewer heart-related problems like irregular heartbeat, blood pressu…

This study is testing a new blood test that looks for cancer DNA to predict how well rectal cancer responds to treatment given before surgery. About 60 adults with locally advanced rectal cancer will provide blood and tissue samples at several time points. The goal is to build a …

This study is for people with locally advanced rectal cancer who are about to receive neoadjuvant therapy (treatment before surgery). Researchers will collect data from 869 participants, including imaging, gut bacteria, and blood tests, to build a model that identifies who can sa…

This study is observing 3,000 people in China who have liver injury caused by drugs or herbs. Researchers want to understand what factors lead to worse outcomes, like liver failure or death. They will use this information to create a model that helps doctors predict and improve r…