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New study scans eyes and brains of kidney patients to uncover hidden links

NCT ID NCT07358572

Knowledge-focused Sponsor: Beijing Friendship Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the eyes, brain, and kidneys affect each other in people with chronic kidney disease (CKD). Researchers will use MRI scans and eye imaging to see if changes in the brain and retina are linked to thinking problems and kidney function. About 1,500 adults with CKD will take part, but no new treatments are being tested.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal early markers of cognitive decline in CKD patients, potentially guiding future monitoring or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health, and results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of a prospective cohort of adult patients with Chronic Kidney Disease (CKD) recruited from a single clinical center. All participants will be selected from patients attending the Department of Nephrology and other relevant clinics at Beijing Friendship Hospital, Capital Medical University. The primary eligibility criteria include an age range of 18 to 70 years and a clinical diagnosis of CKD at any stage (1 through 5). Key exclusions are applied to ensure patient safety and specificity of the observational findings, primarily concerning conditions that contraindicate MRI procedures or represent significant, unstable comorbid systemic, cardiovascular, or neuropsychiatric diseases. A total of 1500 participants meeting these criteria are planned to be enrolled. Each participant will undergo a comprehensive baseline assessment and a follow-up evaluation at 3 years.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 18-70 years. 2. Patients clinically diagnosed with CKD stages 1-5. 3. No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan. Exclusion Criteria: 1. Patients with recent or prior cerebral hemorrhage or cerebral infarction. 2. History of epileptic seizures or psychiatric disorders. 3. Patients with claustrophobia. 4. Pregnant or lactating patients. 5. Presence of other central nervous system diseases (e.g., tumor, trauma). 6. Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction. 7. Any systemic or other diseases deemed unsuitable for clinical trial participation.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Friendship Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100050, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.