Assistance Publique - Hôpitaux De Paris

This study aimed to create and validate a screening tool for auditory processing disorder (APD) in children aged 7 to 13. The tool combines a parent/teacher questionnaire with a short set of hearing tests. The goal was to see if this tool could accurately identify children who ne…

This study looked at whether a CT scan of the colon (CT colonography) is more acceptable to patients than a standard colonoscopy for finding advanced polyps in people at high risk for colorectal cancer. The study included 39 adults aged 18 to 80 with a personal or family history …

This study looked at whether a breathing machine (non-invasive ventilation) could prevent acute chest syndrome, a severe lung complication, in children with sickle cell disease who are in a pain crisis and need strong pain medicine. The machine helps the child breathe without eff…

This study tested whether giving two medications together (oxytocin and misoprostol) is better than oxytocin alone at preventing severe bleeding after a vaginal birth. The trial included over 1,700 women giving birth between 36 and 42 weeks. The study was stopped early, but the g…

This study looked at whether adding clorazepate to standard migraine treatment could provide faster pain relief for people in the emergency room. It included 323 adults with moderate to severe migraine attacks. The study was terminated early, so results are limited.

This study looked at how well the COVID-19 vaccine triggers an immune response in people with autoimmune or inflammatory diseases who take medications that suppress the immune system. Researchers measured antibodies and T-cells after vaccination in 78 adults. The goal was to unde…

This study looked at whether an online video simulator helps new surgeons learn a specific type of prostate cancer surgery (laparoscopic radical prostatectomy). It involved 29 surgeons who had done fewer than 30 such procedures. The main goal was to see if the simulator shortened…

This study aimed to understand how age influences the development of serious health issues like infections, cancer, heart disease, and fractures in people with rheumatoid arthritis (RA). Researchers planned to compare older patients (over 65) with younger adults (18-50) who had R…

This study aimed to track four bone health markers in the blood and urine of multiple myeloma patients receiving intravenous bisphosphonates (bone-strengthening drugs) over 12 months. Only 3 patients were enrolled before the study was terminated, so results are very limited. The …

This study aimed to see if measuring the amount of a drug called mycophenolic acid in the blood could help doctors adjust doses to better treat skin and lung problems in people with systemic sclerosis. Only 2 people joined before the study was stopped early. Because of the small …

This study looked at whether immunosuppressive medications used for rheumatoid arthritis or spondyloarthritis change how the body handles a COVID-19 infection. Researchers compared 150 patients on these drugs to family members with the same infection. The goal was to measure viru…

This study aimed to see if a fall detection device (Vigi'Fall®) improves outcomes for people over 75 who live alone and have fallen before. Researchers planned to compare two groups—one with the device and one without—over 6 months, tracking deaths, hospital visits, and whether t…

This study looked at how numbing medicine spreads during a common knee pain block (adductor canal block) in 30 adults having knee surgery. Researchers used ultrasound to see if the medicine reached nerves behind the knee, which could explain why the block works so well. The goal …