URINARY INCONTINENCE

This study tests a new type of nerve stimulation for Veterans with bladder control problems caused by nerve damage. A small wireless sensor placed in the bladder sends signals to a stimulator that activates only when needed. The goal is to see if this approach can increase time b…

This early-phase study tests whether injecting a patient's own muscle fibers into the bladder neck can safely treat urinary incontinence. Ten adult women with stress incontinence due to a weak sphincter will be monitored for side effects and changes in leakage over a year. The go…

This study looks at how two different types of bladder medication affect thinking, memory, and daily life in women aged 60 and older who have sudden, strong urges to urinate. Participants will be randomly assigned to take one of two drugs or a placebo for 6 months. The goal is to…

This study compares two surgical sling procedures for stress urinary incontinence (leaking urine with activity) in women aged 60 and older. One uses a synthetic mesh tape, the other uses the patient's own tissue. Researchers will check for new pelvic pain at 6 months and cure rat…

This study tests whether doing pelvic floor muscle exercises during pregnancy can reduce the chance of bladder leaks, bowel leaks, and other pelvic floor issues after giving birth. About 734 first-time mothers will be assigned to either a training program or standard care. The ma…

This study compares two treatments for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women who haven't gotten enough relief from conservative care. One group gets a bulking agent injection into the urethra (up to two injections over 12 months)…

This study is checking if a device called the NXT system works well and is safe for measuring bladder function. It will include 180 adults who need a urodynamic study for problems like urinary incontinence or overactive bladder. The main goal is to see if the device measures all …

This study tests a mobile app designed to help women with overactive bladder (OAB) better understand their condition and stick with treatment. About 30 women will use the app to learn about bladder health, track symptoms, and get personalized tips. The goal is to see if the app i…

This early study tests a device called UCon for men with overactive bladder (OAB). The device sends mild electrical pulses through the skin to calm bladder muscles and reduce symptoms like sudden urges, frequent trips to the bathroom, and nighttime urination. About 20 men will us…

This study looks at whether combining Paula exercises with tibial nerve stimulation can help women with stress urinary incontinence. About 52 women who have had at least two vaginal deliveries and leak urine with coughing or sneezing will take part. Researchers will measure chang…

This early study tests a device called UCon that delivers gentle electrical stimulation through the skin to calm overactive bladder and bowel muscles. The goal is to reduce urgent, frequent bathroom trips and leakage. About 20 women will try the device to see if it is safe and im…

This study tests whether a special nurse-led education session and a direct referral to pelvic floor physiotherapy before prostate cancer surgery can reduce urine leakage afterward. About 80 men having prostate removal at Beaumont Hospital will be randomly assigned to either stan…

This study is testing whether two devices used together (EXOMIND and EMSELLA) can help improve depressive symptoms and sexual function in women going through menopause or perimenopause. About 60 women aged 40 and older will receive twelve treatments and complete questionnaires ab…

This study is testing a mobile health app called MyHealtheBladder to help women veterans with urinary incontinence (bladder leaks). The app provides a self-guided program to manage symptoms. Researchers will enroll about 20 women veterans from VA clinics across the U.S. to see ho…

This study tests a new device called PEASY that collects urine without sticky adhesives, using a gentle hold around the foreskin. It aims to reduce pain, itching, and discomfort compared to current diapers or sleeves. About 20 uncircumcised men with incontinence will try it in th…

This study tests two nonsurgical treatments for urinary leakage in new mothers who had a vaginal delivery and are at high risk for pelvic floor problems. About 216 women will be randomly assigned to pelvic floor muscle training, a home biofeedback device, or standard education. T…

This study tests whether a purified CBD medication (Epidiolex) can reduce urinary incontinence in people with a recent spinal cord injury. Twenty participants will take the drug daily for 90 days and track their bladder symptoms using a smartphone app. The goal is to see if CBD i…

This study tests whether a 4-week video education program can reduce urinary incontinence symptoms in women before they begin pelvic floor rehabilitation. About 144 women will either watch the videos or receive a paper handout with similar information. Researchers will compare sy…

This study is testing whether sildenafil (the drug in Viagra) can reduce urine leakage in people with spinal cord injuries. About 24 adults with spinal cord injury who have at least 3 leaks per week will take sildenafil or a placebo for 4 weeks and track their leaks in a diary. T…

This study tests whether two devices used together can help reduce depressive symptoms and urinary incontinence in women who gave birth 2 to 60 months ago. About 60 women will receive twelve treatment sessions and complete questionnaires about their mood, bladder control, and wel…

This study tests whether a small electrical device (TENS) can reduce pain during an outpatient procedure for stress urinary incontinence in women. One hundred women will be randomly assigned to receive either real TENS or a placebo device during the procedure. The goal is to see …

This study looks at whether combining Swiss ball exercises with deep breathing can reduce stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) in pregnant women. About 42 pregnant women with mild to moderate leakage will be split into two groups: one…

This study tests whether adding posture and back exercises to standard pelvic floor training can improve urinary incontinence in women more than pelvic floor exercises alone. 78 women aged 18-65 with stress, urge, or mixed incontinence will be randomly assigned to 12 weeks of eit…

This study looks at whether injecting Botox into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and leaks. About 66 men aged 18-89 with these symptoms will take part. The goal is to see if the combination is s…

This study looks at bacteria in urine, the genital area, and stool of children with overactive bladder and daytime wetting, comparing them to healthy children. Researchers want to see if these bacteria differ between the groups and if they change with treatment or age. About 110 …

This study follows 380 women for one year after vaginal childbirth to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor muscle training can improve symptoms like urine leakage, bowel issues, and vaginal bulging compared to st…

This study is testing a short, 5-question survey called PRAFAB to see if it accurately measures the severity and impact of urinary incontinence in women. Researchers will enroll 63 women diagnosed with urinary incontinence to check if the Turkish version of the survey is valid an…

This study is creating a detailed database of 150 adults with faecal incontinence (leakage of stool) or double incontinence (leakage of both stool and urine). Researchers will compare medical history, symptoms, and results from a special anal pressure test to find out what factor…

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. Researchers will use brain scans to see if a nerve stimulation treatment changes how the brain controls the bladder. About 65 children will take part, and the …

This study looks at whether a 10-minute trampoline session can cause urine leaks or change pelvic floor shape in active women aged 18-40 who say they don't have bladder control issues. Participants will jump on a mini-trampoline while researchers use ultrasound to check for any c…