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Brain scans reveal bladder control secrets in kids

NCT ID NCT05989646

Knowledge-focused Sponsor: Aalborg University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. Researchers use MRI scans to see if brain areas that control the bladder work differently. They also test if a gentle nerve stimulation treatment (TENS) changes brain signals. The goal is to understand how the brain is involved in bladder problems, not to provide a direct treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 65 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2021

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Overactive Bladder as per International Children's Continence Society criteria (cases only). * At least 2 incontinence episodes per week (cases only). * No urinary tract symptoms (healthy participants only). * More than 3 daily urinations. * Normal clinical examination. Exclusion Criteria: * Known urogenital abnormality affecting the lower urinary tract function. * Prior surgery in the urinary tract (except circumcision). * Known neurological diseases or prior cerebral surgery. * Known neuropsychiatric disorders or suspicion of those by screening. * Treatment with pharmacological agents affecting the brain function. * Prior treatment with Enuresis Alarm or Transcutaneous Electrical Nerve Stimulation. * Prior or current treatment with mirabegron or oxybutynin. * Current urinary tract infection. * Current constipation according to Rome IV-criteria or faecal incontinence. * Claustrophobia. * Metallic items in the body contraindicating MRI-scans. * Abnormal uroflowmetry (healthy participants only).

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Conditions

The condition(s) this trial relates to.

Behavioral Symptoms Diurnal Enuresis Elimination Disorders enuresis Lower Urinary Tract Symptoms mental disorder nocturnal enuresis overactive bladder psychiatric disorder Urinary Incontinence urinary system disorder Urination Disorders Urological Manifestations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Behavioral symptoms Daytime wetting Elimination disorders Lower urinary tract symptoms Mental disorders Urinary incontinence Urination disorders Urination involuntary Urologic diseases Urological manifestations

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Pediatrics, Aalborg University Hospital

    RECRUITING

    Aalborg, 9000, Denmark

  • Department of Pediatrics, Aarhus University Hospital

    NOT_YET_RECRUITING

    Aarhus, 8200, Denmark

  • Department of Pediatrics, North Denmark Regional Hospital

    NOT_YET_RECRUITING

    Hjørring, 9800, Denmark

  • Department of Pediatrics, Regional Hospital West Jutland

    NOT_YET_RECRUITING

    Herning, 7400, Denmark

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