TOTAL KNEE ARTHROPLASTY
Clinical trials for TOTAL KNEE ARTHROPLASTY explained in plain language.
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Virtual reality goggles could ease pain during knee recovery
Symptom relief Not yet recruitingThis study looks at whether using virtual reality (VR) during knee exercises after total knee replacement can lower pain and anxiety and increase comfort. About 102 people who had their first knee replacement will be split into two groups: one using VR and one not. Researchers wi…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Celal Bayar University • Aim: Symptom relief
Last updated May 26, 2026 02:58 UTC
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AI coach for joint replacement recovery: better than paper?
Symptom relief Not yet recruitingThis study tests whether an AI-based smartphone app can help people recover faster and more safely after hip or knee replacement surgery. About 106 adults will either use the app for 12 weeks of home exercises or follow the same exercises from a paper brochure. The goal is to see…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Gangnam Severance Hospital • Aim: Symptom relief
Last updated May 26, 2026 02:56 UTC
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New nerve block technique aims to improve recovery after knee replacement
Symptom relief Not yet recruitingThis study tests a new nerve block method (quadri-block) against the standard approach for pain relief after total knee replacement. The goal is to see which method helps patients recover better in the first 24 hours. 100 adults with knee arthritis will be randomly assigned to on…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated May 26, 2026 02:53 UTC
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Knee replacement pain relief: simple injection before surgery may cut opioid use
Symptom relief Not yet recruitingThis study tests whether a numbing injection (genicular nerve block) given before knee replacement surgery can lower pain and the need for strong painkillers afterward. About 70 adults with knee osteoarthritis will be randomly assigned to get either the nerve block or a placebo i…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Helse Møre og Romsdal HF • Aim: Symptom relief
Last updated May 26, 2026 02:52 UTC
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New study aims to find best pain block for knee replacement recovery
Symptom relief Not yet recruitingThis study compares two types of nerve blocks to see which provides better pain relief and faster recovery after total knee replacement. Fifty adults having knee surgery will receive one of two block combinations. The goal is to improve movement and reduce pain after the operatio…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Konya Beyhekim Training and Research Hospital • Aim: Symptom relief
Last updated May 26, 2026 02:48 UTC
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New nursing approach aims to boost knee replacement recovery
Symptom relief Not yet recruitingThis study tests a nursing program based on the ABC-X model for 117 adults aged 30-65 having their first knee replacement. The program helps patients and families manage stress, use support resources, and think positively about recovery. Researchers will measure psychological res…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Symptom relief
Last updated May 26, 2026 02:48 UTC
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New nerve block may cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study tests whether adding a specific nerve block (biceps femoris short head block) to standard pain management reduces the need for morphine after knee replacement surgery. Sixty adults scheduled for knee replacement will be randomly assigned to receive either the extra ner…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Ömer Kayar • Aim: Symptom relief
Last updated May 26, 2026 02:47 UTC
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Who does the nerve block better? surgeon or anesthesiologist?
Symptom relief Not yet recruitingThis study tests whether a surgeon can give a pain-relieving nerve block during knee replacement surgery as effectively as an anesthesiologist using ultrasound. 48 adults having both knees replaced will get one type of block on each knee. The goal is to see if the surgeon's metho…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Yonsei University • Aim: Symptom relief
Last updated May 26, 2026 02:45 UTC
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Knee replacement pain study aims to cut opioid use
Symptom relief Not yet recruitingThis study compares two pain relief methods after total knee replacement: injecting numbing medicine into the knee area versus blocking four nerves in the leg. The goal is to see which method better controls pain and reduces the need for strong painkillers. About 80 adults having…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 26, 2026 02:44 UTC
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One dose before surgery could cut opioid use after knee replacement
Symptom relief Not yet recruitingThis study tests whether a single dose of methadone given just before total knee replacement surgery can improve pain control and reduce the amount of painkillers patients need afterward. About 192 adults aged 21 to 75 having a knee replacement will take part. Researchers will tr…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: AdventHealth • Aim: Symptom relief
Last updated May 26, 2026 02:43 UTC
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Thinking while walking: new knee rehab approach tested
Symptom relief Not yet recruitingThis study looks at whether doing exercises that combine physical movement with mental tasks (like talking while walking) can improve pain, balance, and daily function after total knee replacement. About 40 adults aged 50-65 who had a knee replacement will be split into two group…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated May 22, 2026 14:05 UTC
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Simple stress ball may ease pain after knee surgery
Symptom relief Not yet recruitingThis study looks at whether using a stress ball or doing breathing exercises can reduce pain and keep vital signs stable when a surgical drain is removed after knee replacement. About 105 adults will be split into three groups: stress ball, breathing exercises, or standard care. …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Knee replacement recovery: could a simple pill boost results?
Symptom relief Not yet recruitingThis study looks at whether taking the drug tranexamic acid for up to 7 days after knee replacement surgery can improve pain, function, and how well the knee bends. About 351 adults having a first knee replacement will be randomly assigned to receive the drug or a placebo. The ma…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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AI videos may calm nerves before knee surgery
Symptom relief Not yet recruitingThis study looks at whether using AI-made videos to show patients what happens during knee replacement surgery can lower their anxiety and fear of moving. About 150 adults aged 55 and older who are scheduled for knee replacement will take part. Half will get standard education, a…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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New nerve block may ease pain after knee replacement
Symptom relief Not yet recruitingThis study tests whether adding a new type of nerve block (biceps femoris short head block) to the usual pain management approach can reduce pain and improve recovery after total knee replacement. About 132 adults having knee replacement will be randomly assigned to receive eithe…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Cukurova University • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Knee surgery recovery: does dexamethasone help pain and movement?
Symptom relief Not yet recruitingThis study will follow 99 adults aged 50 to 80 who are having knee replacement surgery. It aims to see if giving the steroid dexamethasone (by mouth or IV) around the time of surgery helps reduce pain, improve mobility, and lessen nausea compared to not giving it. The drug is giv…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Haseki Training and Research Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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3D-Printed gadget aims to perfect knee replacements
Knowledge-focused Not yet recruitingThis study tests a new 3D-printed device that measures how balanced the knee is during total knee replacement surgery. About 50 adults having their first knee replacement will take part. Surgeons will use the device alongside their usual methods, but it won't change how they perf…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated May 26, 2026 02:55 UTC
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Does Same-Day joint surgery affect thinking? new study investigates
Knowledge-focused Not yet recruitingThis study looks at whether older adults (70+) experience changes in thinking skills, like attention and processing speed, after having hip or knee replacement surgery and going home the same day. About 48 participants will take a short cognitive test before surgery and again on …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Odense University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC