TOTAL KNEE ARTHROPLASTY
Clinical trials for TOTAL KNEE ARTHROPLASTY explained in plain language.
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Knee implant checked for 10-Year success in 118 patients
Disease control OngoingThis study looks at how well a specific knee replacement implant (the LEGION Porous HA system) works and holds up over 10 years. Researchers are tracking 118 people who already had this implant to see if it stays in place and how it affects their quality of life. The goal is to m…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated May 26, 2026 02:44 UTC
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Pre-Surgery exercise program aims to boost knee replacement outcomes
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a patient-navigation-based exercise program before knee replacement surgery helps people recover better. 84 adults with knee osteoarthritis scheduled for a total knee replacement will be enrolled. The program focuses on exercises done before surgery to im…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Anna Sun • Aim: Symptom relief
Last updated May 26, 2026 02:57 UTC
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Knee replacement pain study seeks equal relief with two EXPAREL methods
Symptom relief ENROLLING_BY_INVITATIONThis study compares two methods of giving the pain medicine EXPAREL during knee replacement surgery to see if they provide the same amount of pain relief. About 40 adults having knee replacement will receive EXPAREL either as a targeted block or as local infiltration. Participant…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated May 26, 2026 02:46 UTC
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New knee surgery method tested for faster recovery
Symptom relief TerminatedThis study was designed to compare recovery and satisfaction in people getting a total knee replacement using either traditional surgical tools or a newer method called the Newton Knee Protocol. The goal was to see if the new approach leads to better pain relief, function, and sh…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Newton-Wellesley Hospital • Aim: Symptom relief
Last updated May 26, 2026 02:45 UTC
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Knee replacement patients get new pain relief options in head-to-head trial
Symptom relief ENROLLING_BY_INVITATIONThis study compares two types of pain pumps placed in the knee after total knee replacement surgery. 65 adults having knee replacement will be randomly assigned to receive standard pain care alone or standard care plus one of two pain pumps. The goal is to see which approach prov…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated May 26, 2026 02:43 UTC
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Smart glasses may speed up pain relief during knee surgery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether doctors using smart glasses can perform a nerve block (pain relief injection) faster and more easily for people having knee replacement surgery. About 100 adults will take part. The main goal is to see if the glasses reduce the time from needle insertion …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: MetroHealth Medical Center • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Knee replacement study tracks catheter dislodgement
Knowledge-focused OngoingThis observational study looks at how often a small tube that delivers pain medicine near the knee (called an adductor canal catheter) moves out of place the day after total knee replacement surgery. About 100 adults over age 50 will be checked with ultrasound to see if the cathe…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated May 26, 2026 02:56 UTC
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Knee surgery showdown: burr or saw – which tool stays cooler?
Knowledge-focused OngoingThis study looks at how hot the bone gets during knee replacement surgery when using two different cutting tools: a burr (used in robotic surgery) and a saw (used in traditional surgery). Twenty patients having a total knee replacement will be observed, and a special thermometer …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: East Suffolk and North Essex NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Knee implants under the microscope: 10-Year Follow-Up begins
Knowledge-focused OngoingThis study looks at how well two types of knee implants (Legion CR Oxinium and CoCr) hold up over 10 years. Researchers are checking safety and performance in 126 people who already had knee replacement surgery. The goal is to see how long the implants last and if any problems ar…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Smith & Nephew, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 02:43 UTC
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Knee implant showdown: which replacement moves better?
Knowledge-focused TerminatedThis study aimed to compare knee movement in 20 people who had either a MicroPort Medial Pivot or DePuy Attune total knee replacement. Participants were at least six months post-surgery and considered to have successful outcomes. The goal was to measure how the knee implants move…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated May 26, 2026 02:42 UTC
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Your new knee could text your doctor: smart implant study aims to improve recovery
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing a smart knee replacement system that uses sensors and a phone app to track how well people recover after surgery. About 200 adults getting a knee replacement will wear the implant and use the app to send data like walking patterns to their surgeon. The goal …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC