SUBSTANCE USE

This study tests whether telehealth programs can help people manage their alcohol use and improve well-being. About 300 participants will receive either a remote group therapy program or standard care, with follow-up for up to 12 months. The goal is to see if virtual sessions hel…

This study tests a program that combines weekly video chats with a counselor and a mobile app to help young adults (ages 18-29) with HIV keep the virus under control. Participants who are not yet virally suppressed will be randomly assigned to either the program or standard care.…

This study tests a program called Khanya, where trained peers (people who have dealt with substance use themselves) help HIV patients stick to their medication and reduce alcohol or drug use. The program is designed for HIV clinics in South Africa and will be compared to standard…

This study tests a culturally tailored digital program for young Black males aged 15-24 who have been hospitalized for assault injuries. The program aims to reduce aggression, substance use, and improve access to healthcare. Researchers will enroll 300 participants to see if the …

This study compares two ways to help people who are homeless or at risk of homelessness quit smoking: nicotine mouth spray or a medication called Cytisine, both with counseling. About 200 adults in Ottawa and Toronto who smoke or vape will take part for six months. The goal is to…

This study tests whether a collaborative care model—where primary care doctors work with a care team—can help adults reduce their use of opioids, stimulants (like cocaine or meth), and heavy alcohol. About 300 participants will receive this team-based support. The goal is to see …

This study tests a 9-month mentoring program for 8th and 9th graders who have experienced child abuse or neglect and are involved with child welfare. The program pairs teens with trained graduate student mentors who help them set goals in relationships, education, activities, car…

This study looks at whether adding communication skills training and a substance use module to standard couples HIV testing can help male couples reduce drug use and risky sexual behaviors. About 484 male couples will be randomly assigned to different combinations of these add-on…

This study tests a program called Journey of Transformation for Native youth in tenth grade at an off-reservation boarding school. The goal is to see if it can delay or reduce tobacco, alcohol, and other drug use, and improve sexual health. About 182 participants will be followed…

This study tests whether adding trauma coping strategies and peer coaches to a standard mobile alcohol intervention helps young adults (ages 18-25) who have experienced interpersonal trauma reduce heavy drinking. 225 college students are randomly assigned to the enhanced program,…

This study looks at whether giving staff financial bonuses for meeting goals helps them provide better substance use counseling to people with HIV. The study involves 428 participants and focuses on how consistently and well the counseling is delivered. It does not test a new tre…

This study looks at different methods to help primary care clinics screen adults for substance use problems. It involves 144 clinic staff from 48 practices. Researchers compare coaching, team learning, and financial rewards to see which works best.

This study looks at why homeless youth in Ottawa use tobacco, cannabis, and other substances together. Researchers will follow 520 at-risk youth aged 16 and older to understand their substance use patterns. Participants will receive a 6-month program with peer support and a menta…

This study aimed to see if adding trauma coping strategies and peer coaching to a mobile alcohol program helps young adults (ages 18-29) with past interpersonal trauma drink less. Participants would have been randomly assigned to the enhanced program or standard version and follo…

This study looks at whether counseling sessions done over video (telehealth) are practical and well-liked by people with substance use disorder who are not currently getting treatment. About 50 participants will try the program and fill out surveys before, during, and after. The …

This study follows 117 young adults (ages 23–28) who were part of a long-term project since their teenage years. Researchers will use brain scans and surveys to see if certain brain patterns are linked to smoking, drinking, and drug use. The goal is to understand, not treat, how …