SUBSTANCE USE
Clinical trials for SUBSTANCE USE explained in plain language.
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Seeing baby on screen helps moms fight addiction, study finds
Disease control CompletedThis study tested a community-based program to help pregnant women with substance use get better prenatal care and treatment. It used special ultrasounds to help moms connect with their babies, along with education and a personal guide to help them access services. The goal was t…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Phone-Based counseling aims to keep young HIV patients healthy
Disease control CompletedThis study tested whether a counseling program delivered by text and video calls could help young adults (ages 18-29) living with HIV stay engaged in their medical care. The 8-month program aimed to address common challenges like depression and substance use that can interfere wi…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New telehealth program aims to help families navigate dual challenges of psychosis and substance use
Disease control CompletedThis study tested a family training program delivered by video call. It aimed to help family members support a relative who is experiencing early psychosis and using substances like alcohol or cannabis. The goal was to see if the program improved family wellbeing and helped the r…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Mclean Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Peers step in to help youth tackle psychosis and addiction
Disease control CompletedThis study tested a new peer-led support program for young people experiencing their first episode of psychosis who also use substances. The goal was to see if trained peers could help participants reduce substance use and improve their social and daily functioning. The program w…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of Texas at Austin • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC
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New digital tool aims to spot substance use in Spanish-Speaking patients
Diagnosis CompletedThis study aimed to validate a new Spanish-language digital screening tool for identifying tobacco, alcohol, prescription drug, and illicit substance use in primary care settings. It involved 1,000 adult patients who preferred Spanish. Researchers tested how well the new tool's r…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Baylor Research Institute • Aim: Diagnosis
Last updated Apr 03, 2026 19:40 UTC
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AI scans hospital records to uncover hidden addiction
Diagnosis CompletedThis study tested a computer program designed to automatically screen hospitalized patients for substance misuse by reading their electronic health records. The goal was to see if this AI tool could identify more at-risk patients than standard screening methods. Over 64,000 adult…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Diagnosis
Last updated Mar 30, 2026 14:29 UTC
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Hope for youth: community programs tested to stop suicide
Prevention CompletedThis study aimed to find the best way to combine community support programs to prevent suicide and build strength in American Indian youth ages 10-29 who were at risk. Researchers tested different sequences of three approaches: a brief counseling program (New Hope), a cultural co…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Prevention
Last updated Mar 31, 2026 12:12 UTC
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Can a home stop addiction before it starts? landmark trial tests housing as prevention for homeless youth
Prevention CompletedThis study tested whether providing stable housing along with counseling and support services could prevent opioid addiction in homeless young adults. Researchers worked with 240 homeless youth aged 18-24 who were not yet addicted to opioids. They compared two groups: one receive…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Can a Trust-Based program stop At-Risk teens from using opioids?
Prevention CompletedThis study tested a program to prevent opioid and other substance use in teens (ages 15-18) transitioning out of juvenile justice facilities. The program trained a supportive adult in each teen's life to use relationship-building and behavior management techniques. Researchers fo…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Texas Christian University • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Can giving youth a voice stop opioid misuse?
Prevention CompletedThis small pilot study tested whether actively involving young people in community prevention programs helps reduce risks for substance and opioid misuse. Four prevention organizations were randomly assigned to either include youth in their planning and activities or continue the…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Fighting HIV with couples workshops and community support
Prevention CompletedThis study tested a program to prevent new HIV infections among young couples in Cape Town, South Africa, who use alcohol or drugs. It involved 962 people across 24 communities. The program combined a two-day workshop for couples with community education to reduce stigma, aiming …
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: RTI International • Aim: Prevention
Last updated Mar 18, 2026 14:40 UTC
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Can therapy and job help stop the revolving prison door?
Symptom relief CompletedThis study tested whether a special support program helps young men successfully return to society after prison. The program provided therapy for past trauma and practical help with jobs and housing. Researchers wanted to see if this combination improved mental well-being and sta…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Florida State University • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Online program aims to help people cope with chronic pain and substance use
Symptom relief CompletedThis small pilot study tested whether an online self-help program is practical and acceptable for adults with chronic, non-injury related arm or hand pain who also engage in risky substance use. Five participants tried a 4-session video program teaching mind-body skills, pain cop…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Jafar Bakhshaie • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC