SCHIZOAFFECTIVE DISORDER

This study tests a program to reduce or stop anticholinergic medications in adults with schizophrenia, bipolar disorder, or other serious mental illnesses when these drugs are no longer needed. About 111 participants from UPMC clinics will be guided to taper off these medications…

This study looks at whether offering small financial rewards can help people with schizophrenia, bipolar disorder, or substance use disorder stick to their long-acting injectable medications after being hospitalized against their will. About 1,000 participants will be randomly as…

This study tests whether using immersive virtual reality (VR) for cognitive rehabilitation is safe and practical for people with schizophrenia or schizoaffective disorder. Forty participants will either receive VR-based training or continue their usual care. Researchers will meas…

This study tests whether an accelerated schedule of transcranial magnetic stimulation (TMS) is safe and tolerable for people with psychotic disorders like schizophrenia. About 20 adults aged 18-65 with schizophrenia, schizoaffective disorder, or early warning signs of psychosis w…

This study aimed to see if a sublingual film of dexmedetomidine (BXCL501) could quickly reduce agitation in adults with bipolar disorder or schizophrenia visiting the emergency department. It was a single-arm pilot study, but it was withdrawn before enrolling any participants. No…

This study looks at whether adding cognitive remediation (a type of brain training) to standard early psychosis care helps young people function better in work, school, and social settings. About 117 participants from nine OnTrackNY programs will either receive usual care or usua…

This study tests a new program that combines executive function training with cognitive-behavioral social skills training for adults aged 60 and older with schizophrenia or schizoaffective disorder. The goal is to see if the combined approach helps improve daily living skills, su…